Friday, December 21, 2007

University of Toronto case-control study of multiple chemical sensitivity-3: intra-erythrocytic mineral levels.

Occup Med (Lond). 2007 Mar;57(2):137-40. Epub 2006 Oct 17. Links

University of Toronto case-control study of multiple chemical sensitivity-3: intra-erythrocytic mineral levels.

Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada. cornelia.baines@utoronto.ca

BACKGROUND: Multiple chemical sensitivity (MCS) has an estimated American prevalence of 15%, and no consistently abnormal laboratory tests are available to assist in its diagnosis. Some physicians treating MCS patients have observed changes in intra-erythrocytic minerals (IEMs). As co-factors, minerals could influence detoxication of xenobiotics. AIM: To test whether IEM differed comparing MCS cases with controls. METHODS: A total of 408 women meeting validated inclusion and exclusion criteria for MCS participated in this case-control study. RESULTS: No statistically significant differences were observed. However, for copper, chromium, magnesium, molybdenum, sulphur and zinc, mean detectable levels were all lower in cases. No dose-response relationships were found. CONCLUSION: IEM measurements do not appear to provide useful diagnostic markers for MCS.

PMID: 17046989 [PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17046989&itool=iconabstr&itool=pubmed_DocSum

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