Urban air pollution and emergency room admissions for respiratory  symptoms: a case-crossover study in Palermo, Italy.
 Tramuto F, Cusimano R, Cerame G, Vultaggio M, Calamusa G, Maida CM, Vitale  F.  Environ Health. 2011 Apr 13;10(1):31. [Epub ahead of  print]
Abstract
 Abstract
BACKGROUND: Air pollution from vehicular traffic has been associated with  respiratory diseases. In Palermo, the largest metropolitan area in Sicily, urban  air pollution is mainly addressed to traffic-related pollution because of lack  of industrial settlements, and the presence of a temperate climate that  contribute to the limited use of domestic heating plants. This study aimed to  investigate the association between traffic-related air pollution and emergency  room admissions for acute respiratory symptoms.
 METHODS: From January 2004 through December 2007, air pollutant  concentrations and emergency room visits were collected for a case-crossover  study conducted in Palermo, Sicily. Risk estimates of short-term exposures to  particulate matter and gaseous ambient pollutants including carbon monoxide,  nitrogen dioxide, and sulfur dioxide were calculated by using a conditional  logistic regression analysis.
 RESULTS: Emergency departments provided data on 48,519 visits for  respiratory symptoms. Adjusted case-crossover analyses revealed stronger effects  in the warm season for the most part of the pollutants considered, with a  positive association for PM10 (odds ratio = 1.039, 95% confidence interval:  1.020 - 1.059), SO2 (OR=1.068, 95%CI: 1.014 - 1.126), nitrogen dioxide (NO2:  OR=1.043, 95%CI: 1.021 - 1.065), and CO (OR=1.128, 95%CI: 1.074 - 1.184),  especially among females (according to an increase of 10 ug/m3 in PM10, NO2,  SO2, and 1 mg/m3 in CO exposure). A positive association was observed either in  warm or in cold season only for PM10.
 CONCLUSIONS: Our findings suggest that, in our setting, exposure to ambient  levels of air pollution is an important determinant of emergency room (ER)  visits for acute respiratory symptoms, particularly during the warm season. ER  admittance may be considered a good proxy to evaluate the adverse effects of air  pollution on respiratory health.
 PMID: 21489245  [PubMed - as supplied by publisher]