Friday, February 29, 2008

Photocopy machines and occupational antiphospholipid syndrome

Photocopy machines and occupational antiphospholipid syndrome

Bar-Sela S, Shoenfeld Y.

Allergy and Clinical Immunology Clinic, Kupat Holim Meuhedet, Israel.

Isr Med Assoc J. 2008 Jan;10(1):52-4


Two patients who worked for several years in the operation and maintenance of photocopy machines developed an autoimmune disease. In both, early manifestations were thromboembolic phenomena associated with anticardiolipin antibodies. Joint and kidney involvement emerged later, with the appearance of other autoantibodies. These two patients were occupationally exposed to ultraviolet irradiation, ozone emission, and possibly some oxides of heavy metals. To our knowledge this is the first report of occupational autoimmune disease in photocopy machine workers, and the first description of antiphospholipid syndrome as an occupational disease. The possible cause-effect inter-relationship between their occupational exposure and autoimmune disease is discussed.

PMID: 18300574 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/18300574?dopt=AbstractPlus

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