[Comment: Toluene is found in paints, gasoline, synthetic fragrances, nail polish, cigarette smoke, glue, and automobile exhaust. It is also used to make benzene. For more on the health effects and exposure risks of toluene, see the EPA toluene page at http://www.epa.gov/ttn/atw/hlthef/toluene.html]
Neurotoxicity of toluene
Tin-Tin-Win-Shwea and Hidekazu Fujimaki, a,
Toxicology Letters. 
doi:10.1016/j.toxlet.2010.06.022
a Research Center for Environmental Risk, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506, Japan
Abstract
Chemical susceptibility is triggered by a large range of chemicals present both indoors and outdoors including pesticides, cleaning products, perfumes, scented products and cigarette smoke. Health risk after chemical exposure depends on age, sex, genetic factors, socioeconomic status, nutritional status, and environmental factors. Toluene is one of volatile organic chemicals that causes different sensitivity in individuals. Although neurotoxic and immunotoxic effects of toluene has been studied extensively, the underlying mechanism remains obscure. This review highlights the possible neuroimmune factors influencing toluene sensitivity and neurotoxicity in a mouse model.
doi:10.1016/j.toxlet.2010.06.022a Research Center for Environmental Risk, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506, Japan
Abstract
Chemical susceptibility is triggered by a large range of chemicals present both indoors and outdoors including pesticides, cleaning products, perfumes, scented products and cigarette smoke. Health risk after chemical exposure depends on age, sex, genetic factors, socioeconomic status, nutritional status, and environmental factors. Toluene is one of volatile organic chemicals that causes different sensitivity in individuals. Although neurotoxic and immunotoxic effects of toluene has been studied extensively, the underlying mechanism remains obscure. This review highlights the possible neuroimmune factors influencing toluene sensitivity and neurotoxicity in a mouse model.
