Tuesday, April 22, 2008

Allergens Retained in Clothing

Allergens Retained in Clothing

Susan Nedorost; Margaret Kessler; Thomas McCormick

Dermatitis.  2007;18(4):212-214

Abstract

Background: Some patients state compliance with avoidance of identified allergens, yet have persistent dermatitis in areas under tight-fitting clothing.
Objective: To analyze a series of such cases to identify allergens most likely retained in clothing.
Methods: Review of contact dermatitis clinic cases and identification of type and formula weight of allergens involved.
Results: High-formula-weight allergens and allergens present in medicament ointments are difficult to dissolve in laundry detergent and water and may be retained in clothing.
Conclusion: Retention of allergens in clothing, even after washing, may explain recalcitrant dermatitis in a patient who states compliance with avoidance of a seemingly relevant allergen. Dermatologists should consider the possibility of allergen retention in clothing whenever a patient has only partial clearing after at least 1 month of attempted compliance with avoidance of identified allergens. Purchase of new clothing may be required to clear allergic contact dermatitis in this situation.

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