Anticardiolipin antibodies in the sera of patients with diagnosed chronic fatigue syndrome.

Anticardiolipin antibodies in the sera of patients with diagnosed chronic fatigue syndrome.

Journal: J Clin Lab Anal. 2009 Jul 21;23(4):210-212. [Epub ahead of print]

Hokama Y, Campora CE, Hara C, Kuribayashi T, Le Huynh D, Yabusaki K.

Department of Pathology, John A. Burns School of Medicine, University of Hawaii at Mânoa, Honolulu, Hawaii.

NLM Citation: PMID: 19623655

Examination of anticardiolipin antibodies (ACAs) in the sera of patients clinically diagnosed with chronic fatigue syndrome (CFS) using an enzyme-linked immunoassay procedure demonstrated the presence of immunoglobulin M isotypes in 95% of CFS serum samples tested.

The presence of immunoglobulin G and immunoglobulin A isotypes were also detected in a subset of the samples.

Future studies will focus on elucidating whether alterations to mitochondrial inner membranes and/or metabolic functions play a possible role in the expression of ACAs.