"When you choose to use fragrances, chemicals, or pesticides,
You are not simply making a choice for yourself,
You are making a choice for everyone around you."
© MCS America


Sunday, August 31, 2008

Self-Assessed Physical Function Levels Of Women With Fibromyalgia A National Survey.

Womens Health Issues. 2008 Aug 22. [Epub ahead of print]Click here to read Links

Self-Assessed Physical Function Levels Of Women With Fibromyalgia A National Survey.

Health Sciences, California State University, Fullerton, California.

OBJECTIVE: We sought to determine the self-reported physical function level of women with fibromyalgia (FM). METHODS: We performed a secondary analysis using data from an Internet-based survey posted on the National Fibromyalgia Association website. Data used for this study included women (n = 1,735) aged 31-78 years who reported being diagnosed with FM. RESULTS: More than 25% of women reported having difficulty taking care of personal needs and bathing, and >60% reported difficulty doing light household tasks, going up/down 1 flight of stairs, walking (1/2) mile, and lifting or carrying 10 lbs. More than 90% of women reported having difficulty doing heavy household tasks, lifting or carrying 25 lbs, and doing strenuous activities. Women with lower functional ability reported higher levels of fatigue, pain, spasticity, depression, restless legs, balance problems, dizziness, fear of falling, and bladder problems. CONCLUSIONS: The average woman in this sample reported having less functional ability related to activities of daily living and instrumental activities of daily living than the average community-dwelling woman in her 80s. Several symptoms/conditions were found to be associated with functional limitation in women with FM. Targeting these-singly or in clusters-may potentially be important in terms of future interventions.

PMID: 18723374 [PubMed - as supplied by publisher]

The in-home environment and household health: a cross-sectional study of informal urban settlements in northern México.

nt J Environ Res Public Health. 2005 Dec;2(3-4):394-402.
Links

The in-home environment and household health: a cross-sectional study of informal urban settlements in northern México.

http://www.ncbi.nlm.nih.gov/pubmed/16819094?dopt=AbstractPlus

Division of Environmental Health Engineering, Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St., Room E6642, Baltimore, MD 21205, USA. jgraham@jhsph.edu

People living in poverty make up nearly half of the global population and a large proportion of these individuals inhabit cities, living in informal settlements. However, only limited research on in-home environmental exposures and the associated health effects in these communities is available. This research investigates the home environment in unplanned settlements of a rapidly growing city on the U.S.-México border and its impact on the health of households with children under 12 years of age. A cross-sectional design was used to assess household exposures and health outcomes at the household level. A total of 202 households were selected from two informal settlements in the peri-urban region of Ciudad Juárez, México. The following variables were significantly associated with the report of at least one household member experiencing a health outcome in a two week period. Allergies were positively associated with insecticide use inside the home (adjusted Relative Odds (RO), 2.71; 95% confidence interval (CI), 1.2-6.3). Respiratory problems were associated with households using a wood burning stove vs. a gas stove (adjusted RO, 5.64; 95% CI, 1.1-27.9). Diarrhea was negatively associated with presence of a flush toilet in the home (adjusted RO, 0.22; 95% CI,0.1-0.6). Finally, eye irritations were positively associated with indoor tobacco smoke (adjusted RO, 2.23; 95% CI, 1.1-4.5). This research highlights exposures associated with poor living conditions in informal settlements and their associations with detrimental effects on health. More efforts should be made to understand the dynamics of poor urban environments including the health effects of exposures linked with poor housing conditions.

PMID: 16819094 [PubMed - indexed for MEDLINE]

Chronic fatigue syndrome with autoantibodies - The result of an augmented adjuvant effect of hepatitis-B vaccine and silicone implant.

Autoimmun Rev. 2008 Aug 22. [Epub ahead of print]Click here to read Links

Chronic fatigue syndrome with autoantibodies - The result of an augmented adjuvant effect of hepatitis-B vaccine and silicone implant.

Center for Autoimmune Diseases, Department of Medicine 'B', Sheba Medical Center, Israel.

BACKGROUND: Chronic fatigue syndrome (CFS) that defines by prolonged fatigue and other manifestations, was recently integrated into a spectrum of central sensitivity syndromes including several diseases as fibromylagia. CFS etiology is multi-factorial commonly triggered by infectious agents. Vaccines, induce an immune response similarly to infections, and may trigger just like infections autoimmune diseases, CFS and fibromyalgia. Furthermore vaccines contain an adjuvant which enhances their immune stimulation. CASE PRESENTATION: A 56-year-old woman was diagnosed with CFS accompanied by fibromyalgia, demyelination and autoantibodies. Her illness begun following the 2nd dose of hepatitis-B vaccine, and was aggravated by the 3rd vaccination. She underwent silicone breast implantation 6 years before vaccination with no adverse events. However, between the 2nd and 3rd vaccination she suffered a breast injury with local inflammation. Upon explanation of her breast implants silicone leak was observed. DISCUSSION: Vaccines have been reported to precede CFS mainly following exposure to multiple vaccinations (e.g. the Gulf war syndrome), or as an adverse response to the vaccine adjuvant (e.g. the macrophagic myofasciitis syndrome). Silicone is considered an adjuvant to the immune system, and may induce "the adjuvant disease". Silicone implant, especially silicone leak relationship with autoimmunity and CFS has been the focus of considerable debates. CONCLUSION: Our patient illness started following hepatitis-B vaccine, suggesting that it was caused or accelerated by vaccination. In parallel to vaccination our patient suffered from breast injury, which might represent the time of silicone leak. The exposure to the adjuvant, silicone, might have augmented her immune response to the vaccine. To the best of our knowledge this is the first case of combined adverse effect to vaccine and silicone. Vaccine safety in individuals with silicone implants requires further studies.

PMID: 18725327 [PubMed - as supplied by publisher]

Extra digestive manifestations of irritable bowel syndrome: intolerance to drugs?

Dig Dis Sci. 2008 Aug;53(8):2168-76. Epub 2007 Dec 20.Click here to read Links

Extra digestive manifestations of irritable bowel syndrome: intolerance to drugs?

http://www.ncbi.nlm.nih.gov/pubmed/18095162?dopt=AbstractPlus

Centre de Recherche, Centre Hospitalier de l'Université de Montréal-Hôpital Saint-Luc, Montréal, Québec, Canada. pierre.poitras@sympatico.ca

Patients with IBS frequently complain of medication side effects. The goals of this study were to assess the prevalence of drug intolerance as an extra GI manifestation in patients with IBS and to verify the association between drug intolerance and psychological comorbidity. Female patients followed in a tertiary care center completed questionnaires assessing the presence of drug intolerance as well as somatic and psychological extra GI conditions. IBS patients (Rome II criteria; n = 71) were compared to inflammatory bowel disease patients (IBD; n = 96) or to healthy controls (HC; n = 67). The relationship to psychological comorbidity was verified in two different paradigms: (1) by looking at the statistical correlation between drug intolerance and the psychological extra GI symptoms in our IBS patients, and (2) by comparing in a meta-analysis the side effects to placebo (the nocebo effect is presumably increased due to hypervigilance or amplification in psychological disorders) in IBS patients or in patients with comparable medical conditions included in various drug trials approved by Health Canada. Our results show that prevalence of drug intolerance was significantly more elevated in IBS (41% patients) than in HC (7%) or in IBD (27%); somatic and psychological extra GI symptoms were also markedly increased in IBS. In addition, drug intolerance in our IBS patients was significantly associated with somatic comorbidities such as fatigue or multiple symptoms (P < 0.001), but not with psychological factors such as depression, anxiety, mood instability, or sleep disorder. A meta-analysis revealed that the nocebo effect was not different in patients with IBS than in control patients. In conclusion, drug intolerance is a frequent extra GI manifestation of IBS that is not associated with psychological comorbidity; thus, a somatic origin must be explored.

PMID: 18095162 [PubMed - indexed for MEDLINE]

The Influence of the Call with a Mobile Phone on Heart Rate Variability Parameters in Healthy Volunteers

The Influence of the Call with a Mobile Phone on Heart Rate Variability Parameters in Healthy Volunteers
http://www.jstage.jst.go.jp/article/indhealth/46/4/46_409/_article

Rszard ANDRZEJAK1), Rafal POREBA1), Malgorzata POREBA2), Arkadiusz DERKACZ1), Robert SKALIK3), Pawel GAC1), Boguslaw BECK1), Aleksandra STEINMETZ-BECK1) and Witold PILECKI2)

1) Department of Internal Medicine, Occupational Disease and Hypertension, Wroclaw Medical University
2) Department of Pathophysiology, Wroclaw Medical University
3) Department of Physiology, Wroclaw Medical University

(Received May 11, 2007)
(Accepted April 8, 2008)

Abstract: It is possible that electromagnetic field (EMF) generated by mobile phones (MP) may have an influence on the autonomic nervous system (ANS) and modulates the function of circulatory system. The aim of the study was to estimate the influence of the call with a mobile phone on heart rate variability (HRV) in young healthy people.

The time and frequency domain HRV analyses were performed to assess the changes in sympathovagal balance in a group of 32 healthy students with normal electrocardiogram (ECG) and echocardiogram at rest.

The frequency domain variables were computed: ultra low frequency (ULF) power, very low frequency (VLF) power, low frequency (LF) power, high frequency (HF) power and LF/HF ratio was determined. ECG Holter monitoring was recorded in standardized conditions: from 08:00 to 09:00 in the morning in a sitting position, within 20 min periods: before the telephone call (period I), during the call with use of mobile phone (period II), and after the telephone call (period III).

During 20 min call with a mobile phone time domain parameters such as standard deviation of all normal sinus RR intervals (SDNN [ms] - period I: 73.94±25.02, period II: 91.63±35.99, period III: 75.06±27.62; I-II: p<0.05, II-III: p<0.05) and standard deviation of the averaged normal sinus RR intervals for all 5-mm segments (SDANN [ms] - period I: 47.78±22.69, period II: 60.72±27.55, period III: 47.12±23.21; I-II: p<0.05, II-III: p<0.05) were significantly increased.

As well as very low frequency (VLF [ms2] - period I: 456.62±214.13, period II: 566.84±216.99, period III: 477.43±203.94; I-II: p<0.05), low frequency (LF [ms2] - period I: 607.97±201.33, period II: 758.28±307.90, period III: 627.09±220.33; I-II: p<0.01, II-III: p<0.05) and high frequency (HF [ms2] - period I: 538.44±290.63, period II: 730.31±445.78, period III: 590.94±301.64; I-II: p<0.05) components were the highest and the LF/HF ratio (period I: 1.48±0.38, period II: 1.16±0.35, period III: 1.46±0.40; I-II: p<0.05, II-III: p<0.05) was the lowest during a call with a mobile phone.

The tone of the parasympathetic system measured indirectly by analysis of heart rate variability was increased while sympathetic tone was lowered during the call with use of a mobile phone.

It was shown that the call with a mobile phone may change the autonomic balance in healthy subjects. Changes in heart rate variability during the call with a mobile phone could be affected by electromagnetic field but the influence of speaking cannot be excluded.

Full Text at: http://www.jstage.jst.go.jp/article/indhealth/46/4/409/_pdf

Ky words: Mobile phone, Heart rate variability (HRV), Electromagnetic field (EMF), Holter monitoring, Autonomic function

Saturday, August 30, 2008

Fragranced consumer products and undisclosed ingredients.

Researcher Anne Stienemann found hundreds of unlabeled toxic and carcinogenic chemicals in 6 common laundry products and air fresheners. These products emit some substances listed on the Environmental Protection Agency (EPA) list for chemicals with no safe exposure. As such they may lead to multiple chemical sensitivity, environmental illness, asthma, and other illnesses.

The full study may be read at the link below:

Steinemann AC. Fragranced consumer products and undisclosed ingredients. Environ Impact Asses Rev (2008), doi:10.1016/j.eiar.2008.05.002.

http://www.ce.washington.edu/people/faculty/bios/documents/Steinemann2008.pdf

MCS as a biological Illness

Letter to Doctors and Medical Boards Supporting Multiple Chemical Sensitivity (MCS) as a biological Illness (fully cited and scientifically supported)

Website: http://mcs-america.org/MCSPositionStatement.htm

PDF: http://mcs-america.org/MCSPositionStatement.pdf

*This work is copyrighted. Permission granted for personal use in activism provided that original copyright and authorship are maintained. For permission to reprint, mail mailto:admin@mcs-america.org?subject=Position%20Statement.

National and State MCS Support Forums

National and State MCS Support Forums

There are many online list serves and forums for multiple chemical sensitivity (MCS), Environmental Illness and Detoxification. Each forum has a unique flavor and list purpose. Some focus on specific issues, while others are open to varied aspects of chronic illness. A listing of forums may be found here.

http://mcs-america.org/index_files/Forums.htm

Holistic Dentist Referral List by State

Holistic Dentist Referral List by State

Dental care is often challenging for individuals with multiple chemical sensitivity (MCS). Dental materials may cause reactions and should be tested for biocompatibility prior to use. A holistic dentist Is generally more familiar with the needs of individuals with MCS. Some of the dentists on this list are specifically familiar with MCS, others are not. It is recommended that patients and dentists consult with one another prior to beginning any treatment to ensure understanding of the patient's needs and compatibility of patient and dentist.

http://mcs-america.org/dentistlist.pdf

MCS Physician Referral List by State

Physician Referral List by State


Proper medical care is most crucial to recovery for individuals with MCS. Some of the physicians on this list specialize in MCS, others in FM and CFS. It is recommended that patients and doctors consult with one another prior to beginning any treatment to ensure understanding of the patient's needs and compatibility of patient and dentist.

http://mcs-america.org/doctorlist.pdf

MCS Housing Resource List

MCS Housing Resource List

Environmentally Safer Housing
Safer Building & Regulations
Builders and Building Material Suppliers

Other Resources

Free Resource List at: http://mcs-america.org/ReferencesandResources.htm

Disclaimer:
This site is for informational purposes and is not intended to replace the examination, diagnosis and treatment of a licensed physician and no such claims are inferred. MCS America will not be responsible for misuse of this information or the misuse of any information provided by it's member organizations. Articles, citations, links and information are not necessarily the opinion of MCS America and printing does not constitute MCS America's endorsement.

Multiple Chemical Sensitivities (MCS), Environmental Sensitivities (ES), Electrical Hyper-Sensitivities (EHS) and Housing

Multiple Chemical Sensitivities (MCS), Environmental Sensitivities (ES), Electrical Hyper-Sensitivities (EHS) and Housing
http://mcs-america.org/index_files/MCShousing.htm

Section One:
Background

Section Two:
Recommended transitional housing supports for people living with MCS/ES/EHS

Section Three:
Recommendations for safe new developments or retrofits

Section Four:

Individual Unit recommendations

Section Five:
Recommendations for creating the ideal inclusive community environment

References and Resources
Compiled by Linda Sepp
Urbanfengshui @ hotmail.com


Special thanks to AEHA/EHAO, AEHA's Toronto members, Stephen Collette, Jan Bangle,
Lourdes Salvador, and the entire MCS/ES community
Key Words: multiple chemical sensitivity, chemical sensitivity, chemical sensitivities, multiple chemical sensitivities, MCS, EI, environmental illness, sick building syndrome, idiopathic environmental intolerance, fibromyalgia, chronic fatiuge, FM, CFS, mold illness, clinical ecology, alternative medicine, environmental medicine, neuropathy, encephalopathy, toxic, chemical

Wednesday, August 27, 2008

Nerve function and dysfunction in acute intermittent porphyria

Brain Advance Access originally published online on July 17, 2008 Brain 2008 131(9):2510-2519; doi:10.1093/brain/awn152

Nerve function and dysfunction in acute intermittent porphyria
http://brain.oxfordjournals.org/cgi/content/short/131/9/2510

Cindy S.-Y. Lin1,2,3, Arun V. Krishnan1,2, Ming-Jen Lee4, Alessandro S. Zagami1, Hui-Ling You4, Chih-Chao Yang4, Hugh Bostock5 and Matthew C. Kiernan1,2

1Prince of Wales Clinical School, 2Prince of Wales Medical Research Institute, 3School of Medical Sciences, University of New South Wales, Randwick, Sydney, New South Wales, Australia, 4Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan and 5Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London, UK
Correspondence to: Matthew C. Kiernan, Associate Professor, Prince of Wales Medical Research Institute, Barker Street, Randwick, Sydney, New South Wales 2031, Australia E-mail: m.kiernan@unsw.edu.au

Acute intermittent porphyria (AIP) is a rare metabolic disorder characterized by mutations of the porphobilinogen deaminase gene. Clinical manifestations of AIP are caused by the neurotoxic effects of increased porphyrin precursors, although the underlying pathophysiology of porphyric neuropathy remains unclear. To further investigate the neurotoxic effect of porphyrins, excitability measurements (stimulus-response, threshold electrotonus, current–threshold relationship and recovery cycle) of peripheral motor axons were undertaken in 20 AIP subjects combined with the results of genetic screening, biochemical and conventional nerve conduction studies. Compared with controls, excitability measurements from five latent AIP patients were normal, while 13 patients who experienced acute porphyric episodes without clinical neuropathy (AIPWN) showed clear differences in their responses to hyperpolarizing currents (e.g. reduced hyperpolarizing I/V slope, P <>

Key Words: porphyria; haem; nerve excitability; inward rectification (IH); ischaemia
Abbreviations: AIPWN, acute intermittent porphyria without neuropathy; AIPN, acute intermittent prophyric neuropathy; ALA, -aminolevulanic acid; ATP, adenosine triphosphate; APB, abductor pollicis brevis; CMAP, compound muscle action potential; Cr, creatinine; GBS, Guillain Barré syndrome; GH, inward rectifying conductance; HMBS, hydroxymethylbilane synthase gene; IH, hyperpolarizing activated conductance/inward rectification; PBGD, porphobilinogen deaminase; PN, porphyric neuropathy; TA, tibialis anterior; TE, threshold electrotonus

Received November 26, 2007. Revised May 8, 2008. Accepted June 20, 2008.

NEWSLETTER: MCS America News - September 2008

MCSA NEWS
September 2008, Volume 3, Issue 9

Exclusive Housing Edition!

Entire PDF Edition: http://mcs-america.org/september2008.pdf (View, Download, and Print)
NEW! Entire Online Edition:
http://mcs-america.org/mcsanewsseptember2008.htm (View as a Webpage)

Direct Links to Articles Inside This Issue:


Chemical Free Housing, A "Lifeline" to Many
PDF Version: http://mcs-america.org/September2008pg1234.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_Chemical_Free_Housing

Healthy Housing Resources for Multiple Chemical Sensitivity
PDF Version: http://mcs-america.org/September2008pg567.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_Healthy_Housing_Resources


A Proposal to the City of Toronto
Multiple Chemical Sensitivities, Environmental Sensitivities, Electrical Hyper-Sensitivities, and Housing
PDF Version: http://mcs-america.org/September2008pg891011121314151617.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_A_Proposal_to


MCS Homebuyer's Questionnaire
PDF Version: http://mcs-america.org/September2008pg18192021222324.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_MCS_Homebuyer

MCS Housing Resources
PDF Version: http://mcs-america.org/September2008pg2526.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_MCS_Housing_Resources

MCS, Health, and Air Quality
PDF Version: http://mcs-america.org/September2008pg2728.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_MCS,_Health,_and

Is Your Home Cleanser Toxic?
PDF Version: http://mcs-america.org/September2008pg29.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_Is_Your_Home

The Effects of Heating and Cooking in the Home
PDF Version: http://mcs-america.org/September2008pg3031.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_Scientific_Study_The

Scientists Say Household Mold Harms Respiratory Health
PDF Version: http://mcs-america.org/September2008pg32.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_Scientists_Say_Household

Funding Approval for Safe Housing Ottawa Inc
PDF Version: http://mcs-america.org/September2008pg3334.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_Funding_Approved_for

Patient Support and Resources
PDF Version: http://mcs-america.org/September2008pg3536373839.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_Patient_Support_and_

MCS Community News
PDF Version: http://mcs-america.org/September2008pg40.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_MCS_Community_News_

Featured Research Studies
PDF Version: http://mcs-america.org/September2008pg414243.pdf
Online Version: http://mcs-america.org/MCSAnewsSeptember2008.htm#_Featured_MCS_Research



Multiple Chemical Sensitivities America
http://www.mcs-america.org

admin@mcs-america.org

Copyrighted © 2008 MCS America


Monday, August 25, 2008

Multiple Chemical Sensitivity (MCS) - Refuting the Skeptics

Multiple Chemical Sensitivity (MCS) - Refuting the Skeptics
http://www.sylvane.com/blog/multiple-chemical-sensitivity-skeptics/

Even though millions of people are sensitive to certain chemicals, some members of the medical establishment have long viewed multiple chemical sensitivity (MCS) with skepticism.

At a physicians’ conference last year, one immunologist told me that MCS is “all in their heads.”

At the same conference, another physician told me that he has suffered from MCS ever since medical school, when he was exposed to high levels of formaldehyde during dissections.

I know that MCS exists because I have suffered from it.

Entire Article at http://www.sylvane.com/blog/multiple-chemical-sensitivity-skeptics/

Key Words: multiple chemical sensitivity, chemical sensitivity, chemical sensitivities, multiple chemical sensitivities, MCS, EI, environmental illness, sick building syndrome, idiopathic environmental intolerance, fibromyalgia, chronic fatiuge, FM, CFS, mold illness, clinical ecology, alternative medicine, environmental medicine, neuropathy, encephalopathy, toxic, chemical

Sunday, August 24, 2008

Ascorbic acid combats arsenic-induced oxidative stress in mice liver.

Ecotoxicol Environ Saf. 2008 Aug 18. [Epub ahead of print]

Ascorbic acid combats arsenic-induced oxidative stress in mice liver.

http://www.ncbi.nlm.nih.gov/pubmed/18715643?dopt=AbstractPlus
Banerjee P, Bhattacharyya SS, Bhattacharjee N, Pathak S, Boujedaini N, Belon P, Khuda-Bukhsh AR.

Department of Zoology, University of Kalyani, Kalyani-741235, West Bengal, India.
Repeated injections of arsenic trioxide induced oxidative stress and hepatotoxicity in mice as revealed from elevated levels of glutamate oxaloacetate transaminases, glutamate pyruvate transaminases, acid and alkaline phosphatases, lipid peroxidation along with reduction of superoxide dismutase, catalase, reduced glutathione content, glutathione reductase and succinate dehydrogenase activities. The present investigation was undertaken to test whether simultaneous feeding of Vitamin-C can combat hepatotoxicity in arsenic intoxicated mice. Hepatoprotective potential of Vitamin-C was indicated by its ability to restore GSH, SOD, CAT, AcP, AlkP and GRD levels towards near normal. Electron microscopic studies further supported the biochemical findings confirming the hepatoprotective potential of ascorbic acid. Besides, cytogenetical endpoints (chromosome aberrations, micronuclei, mitotic index and sperm head anomaly) were also analyzed. Administration of Vitamin-C alone did not show any sign of toxicity of its own. Based on the present findings, ascorbic acid appears to have protective effects against arsenic toxicity and oxidative stress.

PMID: 18715643 [PubMed - as supplied by publisher]

Key Words: multiple chemical sensitivity, chemical sensitivity, chemical sensitivities, multiple chemical sensitivities, MCS, EI, environmental illness, sick building syndrome, idiopathic environmental intolerance, fibromyalgia, chronic fatiuge, FM, CFS, mold illness, clinical ecology, alternative medicine, environmental medicine, neuropathy, encephalopathy, toxic, chemical

Int Arch Occup Environ Health. 2008 Jul;81(7):881-7. Epub 2007 Dec 6.

Int Arch Occup Environ Health. 2008 Jul;81(7):881-7. Epub 2007 Dec 6.

Prevalence of self-reported symptoms and consequences related to inhalation of airborne chemicals in a Danish general population.

http://www.ncbi.nlm.nih.gov/pubmed/18058120?dopt=AbstractPlus
Berg ND, Linneberg A, Dirksen A, Elberling J.

The Danish Research Centre for Chemical Sensitivities, Gentofte Hospital, University of Copenhagen, Ledreborg Allé 40, 2.th, 2820 Gentofte, Denmark. nidrbe01@geh.regionh.dk
OBJECTIVE: To estimate the prevalence and consequences of self-reported symptoms related to inhalation of airborne chemicals in a Danish general population. METHODS: A random sample of 18-69-year-old individuals (n = 6,000) was drawn from the Danish Civil Registration System. A questionnaire on self-reported symptoms related to inhalation of 11 categories of airborne chemicals was mailed to the population. Respondents who reported symptoms received an additional questionnaire to verify the reported symptoms and to characterise factors related to the initial onset of symptoms. RESULTS: The response rate to the primary questionnaire was 71%. A total of 1,134 individuals (27%, 95% CI 25-28) reported symptoms related to inhalation of airborne chemicals, 141 individuals (3.3%, 95% CI 2.8-3.9) reported adjustments of social life or occupational conditions due to symptoms, whereas 20 individuals (0.5%, 95% CI 0.3-0.7) had made adjustments of both social life and occupational conditions. Women reported more exposures as annoying than men and had more symptoms related to inhalation of airborne chemicals (P < 0.001). However, sex had no effect on the reporting of adjustments of social life or occupational conditions (P = 0.54). CONCLUSION: Symptoms related to inhalation of airborne chemicals were common in this general population, and a minority reported that these symptoms affected social life or occupational conditions. Women as compared to men reported more symptoms but not adjustments of social life or occupational conditions.
PMID: 18058120 [PubMed - indexed for MEDLINE]__._,_.___

Key Words: multiple chemical sensitivity, chemical sensitivity, chemical sensitivities, multiple chemical sensitivities, MCS, EI, environmental illness, sick building syndrome, idiopathic environmental intolerance, fibromyalgia, chronic fatiuge, FM, CFS, mold illness, clinical ecology, alternative medicine, environmental medicine, neuropathy, encephalopathy, toxic, chemical

Saturday, August 23, 2008

Is Dietary Mercury of Neurotoxicological Concern to Wild Polar Bears (Ursus maritimus)?

Environ Toxicol Chem. 2008 Aug 21:1. [Epub ahead of print]

Is Dietary Mercury of Neurotoxicological Concern to Wild Polar Bears (Ursus maritimus)?

http://www.ncbi.nlm.nih.gov/pubmed/18717617?dopt=AbstractPlus

Polar bears are exposed to high concentrations of mercury because they are apex predators in the Arctic ecosystem. While mercury is a potent neurotoxic heavy metal, it is not known whether current exposures are of neurotoxicological concern to polar bears. We tested the hypotheses that: 1) polar bears accumulate levels of mercury in their brains that exceed the estimated lowest observable adverse effect level (20 microg/g dry weight, d.w.) for mammalian wildlife; and 2) such exposures are associated with subtle neurological damage, as determined by measuring neurochemical biomarkers previously shown to be disrupted by mercury in other high-trophic wildlife. Brain stem (medulla oblongata) tissues from 82 polar bears subsistence hunted in East Greenland were studied. Despite surprisingly low levels of mercury in the brain stem region (total mercury = 0.36 +/- 0.12 microg/g d.w.), a significant negative correlation was measured between N-methyl-D-aspartate (NMDA) receptor levels and both total mercury (r = -0.34, p < 0.01) and methylmercury (r = -0.89, p < 0.05). There were no relationships among mercury, selenium, and several other neurochemical biomarkers (dopamine-2, GABA-A, muscarinic cholinergic, nicotinic cholinergic receptors; cholinesterase, monoamine oxidase enzymes). These data show that East Greenland polar bears do not accumulate high levels of mercury in their brain stems. However, decreased levels of NMDA receptors may be one of the most sensitive indicators of mercury's sub-clinical and early effects.

PMID: 18717617 [PubMed - as supplied by publisher]

Structural equation analysis of the causal relationship between health and perceived indoor environment.

Int Arch Occup Environ Health. 2008 May;81(6):769-76. Epub 2007 Oct 5.Click here to read Links

Structural equation analysis of the causal relationship between health and perceived indoor environment.

http://www.ncbi.nlm.nih.gov/pubmed/17917740?dopt=AbstractPlus

Department of Occupational Medicine, Copenhagen University Hospital, Glostrup, Denmark. chabra01@glo.regionh.dk

OBJECTIVES: To explore the temporal relationship and reversed effects between health and perception of the indoor environment using structural equation models. METHODS: The study was a two-phase prospective questionnaire study with a cross-lagged design. Altogether 1,740 adults participated on both occasions. RESULTS: The perceived indoor environment had only weak effects on health at follow-up. However, the results strongly indicated a reversed effect that health problems may lead to increased complaints about the indoor environment. CONCLUSIONS: Structural equation models are powerful analytical tools for disentangling the effects of a specific variable on another in high dimensional data with complex patterns of associations. The analyses confirmed the results of our previous logistic regression analysis about the strong reversed effect. Hence, it is probable that a reversed effect between health and complaints about the indoor environment exists.

PMID: 17917740 [PubMed - indexed for MEDLINE]

Atopy, symptoms and indoor environmental perceptions, tear film stability, nasal patency and lavage biomarkers in university staff.

Int Arch Occup Environ Health. 2008 Jul;81(7):861-72. Epub 2007 Dec 8.Click here to read Links

Atopy, symptoms and indoor environmental perceptions, tear film stability, nasal patency and lavage biomarkers in university staff.

http://www.ncbi.nlm.nih.gov/pubmed/18066577?dopt=AbstractPlus

Section for Occupational Medicine, Department of Public Health and Primary Health Care, University of Bergen, Kalfarveien 31, 5018 Bergen, Norway. jan.bakke@atil.no

OBJECTIVE: Study associations between airway symptoms, complaints on environmental perceptions, atopy definitions and biomarkers including tear film stability (BUT), nasal patency and nasal lavage (NAL). Personal predictors (gender, age, smoking, infections) for the biomarkers as well as associations between the biomarkers were also assessed. METHODS: A cross-sectional study of 173 employees in four university buildings, response rate 86%. Tear film break up time (BUT) was measured by a non-invasive method (NIBUT) and self-reported (SBUT). NAL-analysis included eosinophilic cationic protein (ECP), myeloperoxidase (MPO), lysozyme and albumin. Total serum IgE, and specific IgE using Phadiatop was measured. Data on subjective symptoms, environmental perceptions and background data were collected by use of a questionnaire. Multiple regression analyses were applied. RESULTS: Mean age was 43 years, 21% had weekly ocular, 21% nasal, and 17% laryngeal symptoms. Women had more complaints on environmental perceptions, shorter BUT and less nasal patency. Neither atopy (Phadiatop) nor Total IgE or allergy in the family, but asthma and hay fever was associated with mucosal symptoms or perceptions. Subjects with positive Phadiatop had higher levels of all NAL-biomarkers. Those with ocular symptoms had shorter BUT. Nasal symptoms were related to respiratory infections and laryngeal symptoms to NAL-lysozyme. Perceiving dry air was associated with lower BUT and reduced nasal volume difference before and after decongestion. Older subjects had greater nasal patency, and less atopy. All NAL-biomarkers were positively correlated. Higher lysozyme level was associated with less nasal patency and greater nasal decongestion. CONCLUSIONS: BUT and NAL-lysozyme was associated with ocular, nasal, laryngeal symptoms and indoor environmental perceptions. Ever having had asthma and ever having had hay fever were predictors for symptoms and perceived air quality, respectively. Phadiatop, Total IgE, familiar allergy and ever eczema were not associated to symptoms or perceived environments. Age, gender and Phadiatop were main predictors for ocular and nasal biomarkers.

PMID: 18066577 [PubMed - indexed for MEDLINE]

Neurodevelopmental toxicity of methylmercury: Laboratory animal data and their contribution to human risk assessment.

Regul Toxicol Pharmacol. 2008 Jul;51(2):215-29. Epub 2008 Mar 25.Click here to read Links

Neurodevelopmental toxicity of methylmercury: Laboratory animal data and their contribution to human risk assessment.

http://www.ncbi.nlm.nih.gov/pubmed/18482784?dopt=AbstractPlus

Toxicology Division, University of Pavia, Via Palestro 26, 27100 Pavia, Italy. anna.castoldi@fsm.it

Methylmercury (MeHg) is one of the most significant public health hazards. The clinical findings in the victims of the Japanese and Iraqi outbreaks have disclosed the pronounced susceptibility of the developing brain to MeHg poisoning. This notion has triggered worldwide scientific attention toward the long-term consequences of prenatal exposure on child development in communities with chronic low level dietary exposure. MeHg neurodevelopmental effects have been extensively investigated in laboratory animals under well-controlled exposure conditions. This article provides an updated overview of the main neuromorphological and neurobehavioral changes reported in non-human primates and rodents following developmental exposure to MeHg. Different aspects of MeHg's effects on the immature organism are reported, with particular reference to the delayed onset of symptoms and the persistency of central nervous system (CNS) injury/dysfunction. Particular attention is paid to the comparative toxicity assessment across species, and to the degree of concordance/discordance between human and animal data. The contribution of animal studies to define the role of potential effect modifiers and variables on MeHg dose-response relationships is also addressed. The ultimate goal is to discuss the relevance of laboratory animal results, as a complementary tool to human data, with regard to the human risk assessment process.

PMID: 18482784 [PubMed - indexed for MEDLINE]

Wednesday, August 20, 2008

Etiology of fibromyalgia: The possible role of infection and vaccination.

Autoimmun Rev. 2008 Aug 12. [Epub ahead of print]Click here to read Links

Etiology of fibromyalgia: The possible role of infection and vaccination.

http://www.ncbi.nlm.nih.gov/pubmed/18706528?dopt=AbstractPlus

Department of Internal Medicine H, Soroka Medical Center, Ben Gurion University, Beer Sheva, Israel.

Fibromyalgia syndrome (FMS), a condition characterized by widespread pain and diffuse tenderness, is considered a multifactorial disorder. FMS is now recognized as one of the "central" pain syndromes. Environmental and genetic factors play a role in the pathogenesis of FMS. Various triggers including trauma and stress as well as infections, may precipitate the development of FMS. Certain infections including hepatitis C virus, HIV and Lyme disease have been temporally associated with the development of FMS. There is some evidence for the possible role of vaccinations in triggering the development of FMS and related syndromes, however this association remains to be established.

PMID: 18706528 [PubMed - as supplied by publisher]

The crucial protective role of glutathione against tienilic acid hepatotoxicity in rats.

Toxicol Appl Pharmacol. 2008 Jul 22. [Epub ahead of print]Click here to read Links

The crucial protective role of glutathione against tienilic acid hepatotoxicity in rats.

http://www.ncbi.nlm.nih.gov/pubmed/18708081?dopt=AbstractPlus

Medicinal Safety Research Laboratories, DAIICHI SANKYO CO., LTD., 16-13, Kita-Kasai 1-Chome, Edogawa-ku, Tokyo 134-8630, Japan.

To investigate the hepatotoxic potential of tienilic acid in vivo, we administered a single oral dose of tienilic acid to Sprague-Dawley rats and performed general clinicopathological examinations and hepatic gene expression analysis using Affymetrix microarrays. No change in the serum transaminases was noted at up to 1000 mg/kg, although slight elevation of the serum bile acid and bilirubin, and very mild hepatotoxic changes in morphology were observed. In contrast to the marginal clinicopathological changes, marked upregulation of the genes involved in glutathione biosynthesis [glutathione synthetase and glutamate-cysteine ligase (Gcl)], oxidative stress response [heme oxygenase-1 and NAD(P)H dehydrogenase quinone 1] and phase II drug metabolism (glutathione S-transferase and UDP glycosyltransferase 1A6) were noted after 3 or 6 h post-dosing. The hepatic reduced glutathione level decreased at 3-6 h, and then increased at 24 or 48 h, indicating that the upregulation of NF-E2-related factor 2 (Nrf2)-regulated gene and the late increase in hepatic glutathione are protective responses against the oxidative and/or electrophilic stresses caused by tienilic acid. In a subsequent experiment, tienilic acid in combination with l-buthionine-(S,R)-sulfoximine (BSO), an inhibitor of Gcl caused marked elevation of serum alanine aminotransferase (ALT) with extensive centrilobular hepatocyte necrosis, whereas BSO alone showed no hepatotoxicity. The elevation of ALT by this combination was observed at the same dose levels of tienilic acid as the upregulation of the Nrf2-regulated genes by tienilic acid alone. In conclusion, these results suggest that the impairment of glutathione biosynthesis may play a critical role in the development of tienilic acid hepatotoxicity through extensive oxidative and/or electrophilic stresses.

PMID: 18708081 [PubMed - as supplied by publisher]

Tuesday, August 19, 2008

NEWS: Court Rules for Clean Air, Reverses Bush Administration Rollback

Court Rules for Clean Air, Reverses Bush Administration Rollback

http://action.sierraclub.org/site/MessageViewer?em_id=67401.0

In Sierra Club vs. Environmental Protection Agency, the DC Circuit Court today struck down a Bush administration rule limiting states' ability to enforce the Clean Air Act. The rule blocked states from issuing their own air monitoring requirements for soot, smog, mercury and other types of air pollution from power plants, factories and other stationary sources. As a result states were forced to abide by the lax federal standards, which required virtually no monitoring of dangerous air pollution.

<snip>

Friday, August 15, 2008

Housing and health: intersection of poverty and environmental exposures.

Ann N Y Acad Sci. 2008;1136:276-88.Click here to read Links

Housing and health: intersection of poverty and environmental exposures.

http://www.ncbi.nlm.nih.gov/pubmed/18579887?dopt=AbstractPlus

Columbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, 60 Haven Ave., B-2, New York, NY 10032, USA. var1@columbia.edu

The importance of adequate housing for the maintenance of health and well-being has long been a topic of scientific and public health policy discussion, but the links remain elusive. Here we explore the role of the residential environment in the etiology of illness (specifically asthma) and the persistence of socioeconomic health disparities. Housing conditions, shaped by social forces, affect exposure to physical and chemical "toxicants," thereby translating social adversities into individual illness and population health disparities. We discuss the mediating role of housing in determining health outcomes at multiple levels (social-structural, neighborhood, and individual family). To date, little attention has been paid by most environmental health scientists to the social-structural conditions underlying gross inequities in the distribution of toxic exposures, with even less attention to the processes whereby these social conditions may directly affect susceptibility to the toxic exposures themselves. This chapter goes beyond traditional medical and environmental science models to incorporate a range of social and physical determinants of environmental pollutions, illustrating how these conditions result in health and illness. We focus here on childhood asthma as an example of a serious public health problem that has been associated with low income, minority status, and characteristics of the home environment. We end the chapter with a discussion of the environmental justice movement and the role of housing as a potential agent of change and focus of interventions aimed to reduce the harmful effects of environmental pollutants.

PMID: 18579887 [PubMed - indexed for MEDLINE]

ACTION: Public Comment Needed by Monday, August 18, 2008: MCS Eliminated from the ADA

Public Comment Needed by Monday, August 18, 2008: Chemical Sensitivity Omitted from Americans with Disabilities Act Proposed Regs

http://www.beyondpesticides.org/dailynewsblog/?p=417

(Beyond Pesticides, August 15, 2008)


With a public comment period that ends Monday, August 18, 2008, the U.S. Department of Justice, Disability Rights Section, Civil Rights Division proposes rulemaking that fails to recognize chemical sensitivity (CS) and environmental illnesses as disabilities that may require specific access standards. In a public comment to be submitted next week, Beyond Pesticides urges the Justice Department to specifically include access requirements for those with CS and environmental illnesses in its rulemaking. The organization is urging the public to send comments as well, and invites sign-ons to the Beyond Pesticides' comment.


The comment says, "The proposed rule errs in omitting environmental illness and chemical sensitivity with a justification that people with the illness may have a "sensitivity [that does] not rise to the level needed to constitute a disability." This statement is false and out of step with environmental medicine which diagnoses CS as a chemical-induced illness from which patients suffer with debilitating effects. Similar to other disabilities, a diagnosis reflects a finding that patients cannot function as a result of exposure to neurotoxic chemicals. Eliminating the chemical exposure substantially increases their ability to function and lead normal lives."

The comment continues, "As an organization whose primary focus is pesticides, Beyond Pesticides is in contact with people who are chemically sensitive and are exposed to pesticides, thus substantially limiting their life activities on a regular basis. These are people whose disability is not well understood or accepted by the general public, which is uninformed about the illness. In conveying their concerns to neighbors, employers or landlords they often receive ridicule instead of respect and accommodation. Without mentioning in the text of the accessibility standards of the ADA that those with chemical sensitivities are indeed protected when life activities are substantially limited and that they have specific access requirements, people with CS often cannot get their needs addressed without individual lawsuits to prove their disability. This becomes a burden and barrier to protection."

The comment points to a 1992 memorandum issued by the Department of Housing and Urban Development that recognizes CS and environmental illness as a "handicap," with all the protections afforded those disabled by this illness. The comment reads, "In a 1992 memorandum entitled "Multiple Chemical Sensitivity Disorder and Environmental Illness as Handicaps," the Office of General Counsel in the Department of Housing and Urban Development clearly defines MCS and environmental illness as "handicaps" within the meaning of subsection 802(h) of the Fair Housing Act, 42 U.S.C. Section 3602(h), and the Department's implementing regulations, 24 C.F.R. Section 100.201 (1991)." Rather than equivocate on this debilitating condition, protection should be ensured under the proposed rulemaking beyond one's place of residence."

Beyond Pesticides' comment includes the story and recommendation of a former physical education teacher and coach in Kansas who writes:
With proper accommodation, I would still be teaching and coaching today! Officially recognizing not only the life-changing severity of Multiple Chemical Sensitivity, but also the value of "avoidance" in treating it would help building administrators understand how to keep employees with this disability on the job. I have many friends who are also disabled by MCS. Not one of them wanted to quit their job! But lack of accommodation caused their illness to progress to the point where they could no longer work. MCS takes a huge toll on individual lives and results in unnecessary loss of productivity. I urge you to officially recognize Multiple Chemical Sensitivity/Environmental Illness as a disability requiring accommodation for accessibility. The chemical barriers that prevent those with MCS from entering buildings are every bit as limiting as lack of a ramp would be to someone in a wheelchair. Those with MCS deserve the same rights as other citizens. Recognizing MCS as a "qualified disability" would go a long way toward achieving equal access for everyone!
Beyond Pesticides suggests that the rulemaking include the following language: "Integrated pest management (IPM) practices to protect those disabled with chemical sensitivity (CS) or environmental illnesses and ensure access are required in public facilities or properties to include the following practices: identification of pests and conditions that attract pests; prevention techniques, such as sanitation, vacuuming, structural repair and sealing; monitoring; education and training; approved least toxic chemicals whose use does not, by virtue of its neurotoxic or other properties, impair the abilities of those with CS; and pre-notification and posting of chemical use."

The full text of Beyond Pesticides' comment can be seen here. Thanks to Mary Lamielle of the National Center for Environmental Health Strategies for alerting us to the comment period. Read her comments here.

TAKE ACTION: Access the Federal Register and submit comments electronically here. Click on the yellow dialogue bubble that says "add comments." If you would like to sign on to Beyond Pesticides' comment, please contact Natalie Lounsbury, nlounsbury@beyondpesticides.org, 202-543-5450, by 3:00pm (EDT) on Monday, August 18, 2008.


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NEWS, Science, & Links Summary for the W/E 8/15/2008

Augutst 15, 2008

Psychologists determine what it means to think 'green'
http://www.usatoday.com/life/lifestyle/environment/2008-08-13-green-psychology_N.htm

Sex Hormone Sprays Halted over Cities But.
http://www.i-sis.org.uk/SHSHOCB.php

August 14, 2008

Product Safety Law Signed Today Bans Toxic Toys
http://www.ens-newswire.com/ens/aug2008/2008-08-14-093.asp

"Going Green" When Cleaning Clothes
http://www.cbsnews.com/stories/2008/08/14/cleangreen/main4350297.shtml

ESL - the newest, greenest light bulb around
http://dvice.com/archives/2008/08/esl_the_newest.php

Are Energy-saving Compact Fluorescent Light Bulbs Causing
Headaches?
http://www.healthnewsdigest.com/news/Family_Health_210/Are_Energy-saving_Compact_Fluorescent_Light_Bulbs_Causing_Headaches.shtml

The Going Gets Tough for Organic
http://www.ewg.org/node/27018

Thomas D. Williams: The Depleted Uranium Threat
http://www.scoop.co.nz/stories/HL0808/S00179.htm

Bush signs bill banning lead from children's toys
http://www.ctv.ca/servlet/ArticleNews/story/CTVNews/20080814/lead_ban_080814/20080814?hub=Health

'Toxic Tour' takes in Los Angeles' dirty little secrets
http://afp.google.com/article/ALeqM5gurOYnMTdnTxJjCaT0rNbM5cI5NA

Agent Orange linked to high cancer risk
http://www.azcentral.com/community/westvalley/articles/2008/08/13/20080813gl-nwvchamber0813.html

August 13, 2008

Sick Building Syndrome: Healing Health Facilities
http://www.businessweek.com/print/innovate/content/aug2008/id20080813_845797.htm

How to Reduce BPA Exposure
http://www.ewg.org/node/27009

CMA report: 21,000 will die from pollution in 2008
http://toronto.ctv.ca/servlet/an/local/CTVNews/20080813/smog_report_080813/20080813/?hub=TorontoNewHome

There's no junk science in pesticide regulation
http://network.nationalpost.com/np/blogs/fpcomment/archive/2008/08/13/there-s-no-junk-science-in-pesticide-regulation.aspx

Australian artist in New York offers remedies on environment
http://www.iht.com/bin/printfriendly.php?id=15232862

Sierra Club to test hair for mercury during art fair
http://www.kentucky.com/211/story/489260.html

Pesticides: What you need to know
http://www.easttexasreview.com/story.htm?StoryID=5679

Parents to conduct own EMF readings
http://www.canada.com/deltaoptimist/news/story.html?id=7378967c-bb75-4f54-9d0f-01dbe1919928

Malibu dentist aims to ban mercury amalgam fillings
http://www.malibutimes.com/articles/2008/08/13/news/news2.txt

Population Bomb Author's Fix For Next Extinction: Educate Women
http://www.sciam.com/article.cfm?id=sixth-extinction

August 12, 2008

Is your home damaging your health?
http://aww.ninemsn.com.au/article.aspx?id=612449

Berkeley Scientists: World In 'Mass Extinction Spasm'
http://www.nbc11.com/news/17171725/detail.html

Away With Weeds: Synthetic vs. Non-Toxic Weed Control
http://www.telluridewatch.com/pages/full_story?article-Away-With-Weeds-Synthetic-vs-Non-Toxic-Weed-Control%20=&page_label=news&id=178030-Away-With-Weeds-Synthetic-vs-Non-Toxic-Weed-Control&widget=push&instance=secondary_stories_left_column&open=&

Eco-labels on food can cook up confusion
http://www.democratandchronicle.com/apps/pbcs.dll/article?AID=/20080812/LIVING/808120303/1032

Micro loans help pay for controversial autism treatments
http://www.ocregister.com/articles/tuncan-autism-treatment-2121310-treatments-pay

Bernie Mac's death puts sarcoidosis in spotlight
http://www.chicagotribune.com/features/lifestyle/health/chi-sarcoidosisaug12,0,5966562.story

August 11, 2008

Prescriptions for Health, the Environmental Kind
http://www.nytimes.com/2008/08/12/health/12clin.html?_r=1&adxnnl=1&oref=slogin&ref=science&adxnnlx=1218564993-1fEQf4nvySM6bfvFJ4OcFg

Dialing up cancer?
http://www.cadillacnews.com/story_news/?story_id=374940&year=2008

What's in a fragrance? Labels aren't required to say
http://www.sfgate.com/cgi-bin/blogs/chrongreen/detail?&entry_id=28990

Children's sunscreens may not be effective
http://healthzone.ca/health/article/475813

Dow's Dioxins: Saga of pollution, politics, and struggle over cleanup has
nationwide implications
http://pubs.acs.org/cen/coverstory/86/8632cover.html

August 10, 2008

Calif. lawmakers weigh ban on chemical found in baby bottles, although
danger is in dispute
http://www.newsday.com/news/nationworld/nation/ats-ap-bisphenol-banaug10,0,4397098.story

Mold forces family out of Bradley Beach home
http://www.app.com/apps/pbcs.dll/article?AID=/20080810/NEWS01/808100410/1004

August 9, 2008

Eleven fall ill after bug spray incident at Pearson
http://toronto.ctv.ca/servlet/an/local/CTVNews/20080809/bug_spray_incident_080908/20080809/?hub=TorontoNewHome

Local fibromyalgia support groups are hard to find
http://www.independentmail.com/news/2008/aug/09/local-fibromyalgia-support-groups-are-hard-find/

Our chemical paranoia
http://www.canada.com/ottawacitizen/news/story.html?id=26e9ec42-2d45-4f43-a67d-ba4a2452870a

Lawyer threatens suit over 'very sick' Broward County Courthouse
http://www.sun-sentinel.com/news/local/southflorida/sfl-flbcourt0809sbaug09,0,4563742.story

Inhalational Diesel Exhaust Exposure in Submariners: Observational Study
http://www.redorbit.com/news/health/1516570/inhalational_diesel_exhaust_exposure_in_submariners_observational_study/

No matter what flame retardant is used, it shows up in the environment
http://www.theglobeandmail.com/servlet/story/LAC.20080809.ZOE09/TPStory/Environment

Energy-saving light bulbs carry risk
http://www.tucsoncitizen.com/daily/local/93203.php

August 8, 2008

Chemicals are placing our food supplies at great risk
http://www.elpasotimes.com/opinion/ci_10130946

Family: Prison Worker's Death was Caused by Toxic Dust
http://www.abcnews.go.com/print?id=5540890

An invisible illness: Chronic Fatigue Syndrome
http://www.thesuburbanite.com/communities/x907752099/An-invisible-illness-Chronic-Fatigue-Syndrome

New clinic, doctor for Anniston PCB child victims
http://www.dailycomet.com/article/20080808/APN/808080927

Scented consumer products contain undisclosed toxic compounds: study
http://www.cbc.ca/consumer/story/2008/08/08/fragrance-study.html

And another thing ... Getting on a soapbox
http://www.dailylocal.com/site/news.cfm?newsid=19900115&BRD=1671&PAG=461&dept_id=635533&rfi=6

Levels of scents in breast milk related to women's product use
http://www.sciencenews.org/view/generic/id/35041/title/Perfumed_mother's_milk

July 31, 2008

In Retreat: Don't give government's "susceptible subset" strategy a chance.
http://spectrumpublications.com/index.php/component/option,com_mojo/Itemid,/p,24

Links

AAEM Statement: Molds and Mycotoxins (Toxic Molds) in Human Health
http://www.aaemonline.org/images/MoldStatement.pdf

Liberty School Mold
http://www.libertyschoolmold.com/

American Academy of Environmental Medicine
Molds and Mycotoxins (Toxic Molds) in Human Health
http://www.aaemonline.org/images/MoldStatement.pdf

Scientific Studies

From the Learning and Developmental Disabilities Initiative. Policy
Implications Based on the Scientific Consensus Statement on Environmental
Agents Associated with Neurodevelopmental Disorders
July 31, 2008
http://www.iceh.org/pdfs/LDDI/LDDIPolicyStatement.pdf

Learning and Developmental Disabilities Initiative. Scientific Consensus
Statement on Environmental Agents Associated with Neurodevelopmental
Disorders Developed by the Collaborative on Health and the Environment's
February 20, 2008 (revised July 1, 2008)
http://www.iceh.org/pdfs/LDDI/LDDIStatement.pdf

Fibromyalgia syndrome: a relevant recent construction of an ancient
condition?
http://www.ncbi.nlm.nih.gov/pubmed/18685409?dopt=AbstractPlus

Treating Chronic Fatigue states as a disease of the regulation of energy
metabolism.
http://www.ncbi.nlm.nih.gov/pubmed/18684570?dopt=AbstractPlus

Studying the effects of mobile phone use on the auditory system and the
central nervous system: a review of the literature and future directions.
http://www.ncbi.nlm.nih.gov/pubmed/18504596?ordinalpos=23&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Volatile pollutants emitted from selected liquid household products.
http://www.ncbi.nlm.nih.gov/pubmed/18688669?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Hawai'i air quality monitoring assessment: some effects of Hawai'i's
smoke-free work and public places law.
http://www.ncbi.nlm.nih.gov/pubmed/18678206?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Professional judgment and the interpretation of viable mold air sampling
data.
http://www.ncbi.nlm.nih.gov/pubmed/18668405?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Results of a residential indoor PM sampling program before and after a
woodstove changeout.
http://www.ncbi.nlm.nih.gov/pubmed/18665872?ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Awareness of health effects of cooking smoke among women in the Gondar
Region of Ethiopia: a pilot survey.
http://www.ncbi.nlm.nih.gov/pubmed/18644103?ordinalpos=12&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Exposure to indoor mould and children's respiratory health in the PATY
study.
http://www.ncbi.nlm.nih.gov/pubmed/18621956?ordinalpos=20&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

[Health effects of nanoparticles and nanomaterials (II) methods for
measurement of nanoparticles and their presence in the air]
http://www.ncbi.nlm.nih.gov/pubmed/18567372?dopt=AbstractPlus

Lourdes Salvador
www.mcs-america.org

Disclaimer:
Articles and links are not necessarily the opinion of MCS America, Lourdes
Salvador, and/or the volunteers who assemble this information. We will be
not responsible for misuse of this information. Posting does not constitute
endorsement. We have no financial interest in anything posted . This post is
provided free of charge via volunteer effort.

NEWS: President Signs Phthalate and Lead Bans Into Law

President Signs Phthalate Ban Into Law

http://www.blogger.com/

President Bush signed a federal bill today that bans six toxic phthalates from children's products. His signature bolsters Congress overwhelming support for this legislation, and sends a clear message that toxic chemicals have no place in toys.

Bush signs bill banning lead from children's toys

http://www.ctv.ca/servlet/ArticleNews/story/CTVNews/20080814/lead_ban_080814/20080814?hub=Health

President George W. Bush on Thursday signed consumer-safety legislation that bans lead from children's toys, imposing the toughest standard in the world.

The new law prohibits lead, beyond minute levels, in products for children 12 or younger. Lead paint was a major factor in the recall of 45 million toys and children's items last year, many from China.

Thursday, August 14, 2008

Amitriptyline in the treatment of fibromyalgia: a systematic review of its efficacy.

Rheumatology (Oxford). 2008 Aug 12. [Epub ahead of print]

Amitriptyline in the treatment of fibromyalgia: a systematic review of its efficacy.

http://www.ncbi.nlm.nih.gov/pubmed/18697829?dopt=AbstractPlus

Iberoamerican Cochrane Center, Public Health and Clinical Epidemiology Service, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Universitat Autònoma de Barcelona, Barcelona, Kovacs Foundation, Palma de Mallorca, CIBER Epidemiología y Salud Pública (CIBERESP), Spain, Washington Hospital Center, WA, USA and Hospital de la Vall d'Hebron, Barcelona, Spain.

The objective of this study was to assess the efficacy and safety of amitriptyline as a treatment of FM. A comprehensive computerized search in Medline (Pubmed), EMBASE and The Cochrane Library was performed. Randomized controlled trials (RCTs) comparing amitriptyline vs placebo in adult patients suffering from FM were identified, the methodological quality was assessed and the results of the main outcomes were evaluated. Ten RCTs were identified. Large clinical variability and statistical heterogeneity precluded quantitative meta-analysis. Overall, the study quality was moderate to high. Amitriptyline 25 mg/day (six RCTs) demonstrated a therapeutic response compared with placebo in the domains of pain, sleep, fatigue and overall patient and investigator impression. This benefit was generally seen at 6-8 weeks of treatment but no effect was noted at 12 weeks. Amitriptyline 50 mg/day (four RCTs) did not demonstrate a therapeutic effect compared with placebo. Neither dose of amitriptyline had an effect on tender points count. No clear statements on adverse events with amitriptyline can be made due to inconsistencies in data among the studies. A definitive clinical recommendation regarding the efficacy of amitriptyline for FM symptoms cannot be made. There is some evidence to support the short-term efficacy of amitriptyline 25 mg/day in FM. There is no evidence to support the efficacy of amitriptyline at higher doses or for periods >8 weeks. More stringent RCTs with longer follow-up periods are required to determine the long-term efficacy and safety of the amitriptyline and define its role in the multidisciplinary management of FM.

PMID: 18697829 [PubMed - as supplied by publisher]

Sunday, August 10, 2008

Exposure to indoor mould and children's respiratory health in the PATY study.

J Epidemiol Community Health. 2008 Aug;62(8):708-14.Click here to read Links

Exposure to indoor mould and children's respiratory health in the PATY study.

Environmental Health Unit, NCPHP, Sofia, Bulgaria.

BACKGROUND: Living in a damp or mouldy home reportedly damages children's respiratory health, yet mould appears not to be a prominent risk factor in the public's perception. Analyses of data on over 58,000 children from the Pollution and the Young (PATY) study are presented. In this collaboration, researchers from 12 cross-sectional studies pooled their data to assess the effects of air quality on a spectrum of children's respiratory disorders. METHOD: Original studies were conducted in Russia, North America and 10 countries in Eastern and Western Europe. Pooled analyses were restricted to children aged 6-12 years. Associations between visible mould reported in the household and a spectrum of eight respiratory and allergic symptoms were estimated within each study. Logistic regressions were used, controlling for individual risk factors and for study area. Heterogeneity between study-specific results and mean effects (allowing for heterogeneity) were estimated using meta-analysis. RESULTS: Visible mould was reported by 13.9% of respondents in Russia, increasing to 39.1% in North America. Positive associations between exposure to mould and children's respiratory health were seen with considerable consistency across studies and across outcomes. Confounder-adjusted combined ORs ranged from 1.30 (95% CI 1.22 to 1.39) for "nocturnal cough" to 1.50 (1.31 to 1.73) for "morning cough". Evidence of stronger effects in more crowded households was statistically significant for only asthma and sensitivity to inhaled allergens. No consistent interactions between mould and age, sex or parental smoking were found. CONCLUSION: Indoor mould exposure was consistently associated with adverse respiratory health outcomes in children living in these diverse countries.

PMID: 18621956 [PubMed - in process]

Awareness of health effects of cooking smoke among women in the Gondar Region of Ethiopia: a pilot survey.

BMC Int Health Hum Rights. 2008 Jul 18;8:10.Click here to read Click here to read Links

Awareness of health effects of cooking smoke among women in the Gondar Region of Ethiopia: a pilot survey.

Department of Infection, Immunity and Inflammation, Division of Child Health, University of Leicester, UK. nsk@doctors.org.uk.

ABSTRACT: BACKGROUND: The burning of biomass fuels results in exposure to high levels of indoor air pollution, with consequent health effects. Possible interventions to reduce the exposure include changing cooking practices and introduction of smoke-free stoves supported by health education. Social, cultural and financial constraints are major challenges to implementation and success of interventions. The objective of this study is to determine awareness of women in Gondar, Ethiopia to the harmful health effects of cooking smoke and to assess their willingness to change cooking practices. METHODS: We used a single, administered questionnaire which included questions on household circumstances, general health, awareness of health impact of cooking smoke and willingness to change. We interviewed 15 women from each of rural, urban-traditional and middle class backgrounds. RESULTS: Eighty percent of rural women cooked indoors using biomass fuel with no ventilation. Rural women reported two to three times more respiratory disease in their children and in themselves compared to the other two groups. Although aware of the negative effect of smoke on their own health, only 20% of participants realised it caused problems in children, and 13% thought it was a cause for concern. Once aware of adverse effects, women were willing to change cooking practices but were unable to afford cleaner fuels or improved stoves. CONCLUSION: Increasing the awareness of the health-effects of indoor biomass cooking smoke may be the first step in implementing a programme to reduce exposure.

PMID: 18644103 [PubMed - in process]

Results of a residential indoor PM sampling program before and after a woodstove changeout.

Indoor Air. 2008 Jul 28. [Epub ahead of print] Links

Results of a residential indoor PM sampling program before and after a woodstove changeout.

Center for Environmental Health Sciences, The University of Montana-Missoula, MT, USA.

During 2005-2007, a woodstove changeout program was conducted in a Rocky Mountain valley community in an effort to reduce ambient levels of PM(2.5). In addition to changes in ambient PM(2.5), an opportunity was provided to evaluate the changes in indoor air quality when old stoves were replaced with US Environmental Protection Agency (EPA)-certified woodstoves. PM(2.5) samples were measured in 16 homes prior to and following the changeout. For each sampling event, PM(2.5) mass was continuously measured throughout the 24-h sampling periods, and organic/elemental carbon (OC/EC) and associated chemical markers of woodsmoke were measured from quartz filters. Results showed that average PM(2.5) concentrations and maximum PM(2.5) concentrations were reduced by 71% and 76%, respectively (as measured by TSI DustTraks). Levoglucosan was reduced by 45% following the introduction of the new woodstove. However, the concentrations of resin acids, natural chemicals found in the bark of wood, were increased following the introduction of the new woodstove. There were no discernible trends in methoxphenol levels, likely due to the semi-volatile nature of the species that were measured. Although there is some uncertainty in this study regarding the amount of ambient PM infiltration to the indoor environment, these findings demonstrated a large impact on indoor air quality following this intervention. Practical Implications Emissions from residential woodstoves are an important air quality issue (both indoors and ambient) in many regions throughout the US and the world. More specifically, woodstoves have been identified as a major source of PM(2.5) in valley locations throughout the Northern Rocky Mountains, where biomass combustion is the predominant source of home heating. In this study, we present results that demonstrate the dramatic reduction in PM(2.5) concentrations (as measured by TSI, Inc. DustTrak PM(2.5) air samplers) inside homes following the replacement of old, polluting woodstove with new EPA-certified woodstoves.

PMID: 18665872 [PubMed - as supplied by publisher]

Professional judgment and the interpretation of viable mold air sampling data.

J Occup Environ Hyg. 2008 Oct;5(10):656-63.Click here to read Links

Professional judgment and the interpretation of viable mold air sampling data.

Occupational and Environmental Health, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma 73190, USA. david-johnson@ouhsc.edu

Although mold air sampling is technically straightforward, interpreting the results to decide if there is an indoor source is not. Applying formal statistical tests to mold sampling data is an error-prone practice due to the extreme data variability. With neither established exposure limits nor useful statistical techniques, indoor air quality investigators often must rely on their professional judgment, but the lack of a consensus "decision strategy" incorporating explicit decision criteria requires professionals to establish their own personal set of criteria when interpreting air sampling data. This study examined the level of agreement among indoor air quality practitioners in their evaluation of airborne mold sampling data and explored differences in inter-evaluator assessments. Eighteen investigators independently judged 30 sets of viable mold air sampling results to indicate: "definite indoor mold source," "likely indoor mold source," "not enough information to decide," "likely no indoor mold source," or "definitely no indoor mold source." Kappa coefficient analysis indicated weak inter-observer reliability, and comparison of evaluator mean scores showed clear inter-evaluator differences in their overall scoring patterns. The responses were modeled on indicator "traits" of the data sets using a generalized, linear mixed model approach and showed several traits to be associated with respondents' ratings, but they also demonstrated distinct and divergent inter-evaluator response patterns. Conclusions were that there was only weak overall agreement in evaluation of the mold sampling data, that particular traits of the data were associated with the conclusions reached, and that there were substantial inter-evaluator differences that were likely due to differences in the personal decision criteria employed by the individual evaluators. The overall conclusion was that there is a need for additional work to rigorously explore the constellation of decision criteria, the weightings employed by individual practitioners, and the rationale under which criteria are adopted as first steps toward the larger goal of developing a consensus mold decision strategy.

PMID: 18668405 [PubMed - in process]

Hawai'i air quality monitoring assessment: some effects of Hawai'i's smoke-free work and public places law.

Hawaii Med J. 2008 Jun;67(6):149-55. Links

Hawai'i air quality monitoring assessment: some effects of Hawai'i's smoke-free work and public places law.

Community Health Division, Hawai'i State Department of Health, 1250 Punchbowl St., #218 Honolulu, HI 96813, USA. ann.m.pobutsky@doh.hawaii.gov

In November 2006, the Smoke-Free Work and Public Places Law passed to protect people from secondhand smoke in Hawai'i. An air-quality monitoring assessment to determine the difference this law made in air quality was conducted at 15 bars/restaurants. Levels of particulate matter (PM2.5) at enclosed (indoor) venues fell 90% after implementation of the law while partially enclosed restaurants/bars were all below the EPA 24 hour average limit both before and after the law.

PMID: 18678206 [PubMed - in process]

Volatile pollutants emitted from selected liquid household products.

Environ Sci Pollut Res Int. 2008 Aug 8. [Epub ahead of print]

Volatile pollutants emitted from selected liquid household products.

Department of Indoor Environment, National Institute of Environment Research, Incheon, South Korea.

BACKGROUND, AIM, AND SCOPE: To identify household products that may be potential sources of indoor air pollution, the chemical composition emitted from the products should be surveyed. Although this kind of survey has been conducted by certain research groups in Western Europe and the USA, there is still limited information in scientific literature. Moreover, chemical components and their proportions of household products are suspected to be different with different manufacturers. Consequently, the current study evaluated the emission composition for 42 liquid household products sold in Korea, focusing on five product classes (deodorizers, household cleaners, color removers, pesticides, and polishes). MATERIALS AND METHODS: The present study included two phase experiments. First, the chemical components and their proportions in household products were determined using a gas chromatograph and mass spectrometer system. For the 19 target compounds screened by the first phase of the experiment and other selection criteria, the second phase was done to identify their proportions in the purged-gas phase. RESULTS: The number of chemicals in the household products surveyed ranged from 9 to 113. Eight (product class of pesticides) to 17 (product class of cleaning products) compounds were detected in the purged-gas phase of each product class. Several compounds were identified in more than one product class. Six chemicals (acetone, ethanol, limonene, perchloroethylene (PCE), phenol, and 1-propanol) were identified in all five product classes. There were 13 analytes occurring with a frequency of more than 10% in the household products: limonene (76.2%), ethanol (71.4%), PCE (66.7%), phenol (40.5%), 1-propanol (35.7%), decane (33%), acetone (28.6%), toluene (19.0%), 2-butoxy ethanol (16.7%), o-xylene (16.7%), chlorobenzene (14.3%), ethylbenzene (11.9%), and hexane (11.9%). All of the 42 household products analyzed were found to contain one or more of the 19 compounds. DISCUSSION: The chemical composition varied broadly along with the product classes or product categories, and it was different from that reported in other studies abroad, although certain target chemicals were identified in both studies. This finding supports an assertion that chemical components emitted from household products may be different in different products and with different manufacturers. The chlorinated pollutants identified in the present study have not been reported to be components of cleaning products in papers published since the early 1990s. Limonene was identified as having the highest occurrence in the household products in the present study, although it was not detected in any of 67 household products sold in the U.S. CONCLUSIONS: The emission composition of selected household products was successfully examined by purge-and-trap analysis. Along with other exposure information such as use pattern of household products and the indoor climate, this composition data can be used to estimate personal exposure levels of building occupants. This exposure data can be employed to link environmental exposure to health risk. It is noteworthy that many liquid household products sold in Korea emitted several toxic aromatic and chlorinated organic compounds. Moreover, the current finding suggests that product types and manufacturers should be considered, when evaluating building occupants' exposure to chemical components emitted from household products. RECOMMENDATIONS AND PERSPECTIVES: The current findings can provide valuable information for the semiquantitative estimation of the population inhalation exposure to these compounds in indoor environments and for the selection of safer household products. However, although the chemical composition is known, the emissions of household products might include compounds formed during the use of the product or compounds not identified as ingredients by this study. Accordingly, further studies are required, and testing must be done to determine the actual composition being emitted. Similar to eco-labeling of shampoos, shower gels, and foam baths proposed by a previous study, eco-labeling of other household products is suggested.

PMID: 18688669 [PubMed - as supplied by publisher]

Occupational exposures and non-Hodgkin's lymphoma: Canadian case-control study.

Environ Health. 2008 Aug 7;7(1):44. [Epub ahead of print]

Occupational exposures and non-Hodgkin's lymphoma: Canadian case-control study.

ABSTRACT: BACKGROUND: The objective was to study the association between Non-Hodgkin's Lymphoma (NHL) and occupational exposures related to long held occupations among males in six provinces of Canada. METHODS: A population based case-control study was conducted from 1991 to 1994. Males with newly diagnosed NHL (ICD-10) were stratified by province of residence and age group. A total of 513 incident cases and 1506 population based controls were included in the analysis. Conditional logistic regression was conducted to fit statistical models. RESULTS: Based on conditional logistic regression modeling, the following factors independently increased the risk of NHL: farmer and machinist as long held occupations; constant exposure to diesel exhaust fumes; constant exposure to ionizing radiation (radium); and personal history of another cancer. Men who had worked for 20 years or more as farmer and machinist were the most likely to develop NHL. CONCLUSIONS: An increased risk of developing NHL is associated with the following: long held occupations of farmer and machinist; exposure to diesel fumes; and exposure to ionizing radiation (radium). The risk of NHL increased with the duration of employment as a farmer or machinist.

PMID: 18687133 [PubMed - as supplied by publisher]

NEWS: Industry fights effort to ban chemical in baby products

Industry fights effort to ban chemical in baby products

State official, scientist criticize a chemical-industry backed campaign to keep potentially dangerous baby products on the market.

A chemical industry-backed lobbying group has mounted a statewide campaign to convince Californians that a potentially dangerous compound found in baby products and canned goods is safe, and warns that if efforts to ban it are successful, "going to a grocery store may never be the same."  State officials and scientists say the ads are misleading and designed to scare consumers into keeping products that could harm children on the market.

<snip>

"This kind of stuff just drives people in science crazy," he said. "(Scientists) live in a world where if you don't tell the truth, you're excommunicated. From the tobacco industry on down, corporations figure that anything they do to protect their profits is O.K."

Is chronic fatigue syndrome caused by a rare brain infection of a common, normally benign virus?

Medical Hypotheses. Vol. 71,#2,pp 270-274;August 2008
Is chronic fatigue syndrome caused by a rare brain infection of a common, normally benign virus?
http://www.sciencedirect.com/science/journal/03069877

Bjorn Grinde(*)
* National Institute of Public Health, P.O. Box 4404, Nydalen, 0403 Oslo, Norway
  Tel.: +47 22042420; fax: +47 22042447. E-mail address: bjgr@fhi.no

Received 15 February 2008; accepted 10 March 2008

Summary

Chronic fatigue syndrome (CFS) is a disabling disease of unknown aetiology. A
variety of factors have been suggested as possible causes. Although the
symptoms and clinical findings are heterogeneous, the syndrome is
sufficiently distinct, at least in relation to the more obvious cases, that a
common explanation seems likely. In this paper, it is proposed that the
disease is caused by a ubiquitous, but normally benign virus, e.g., one of
the circoviruses. Circoviruses are chronically present in a majority of
people, but are rarely tested for diagnostically. Normally these viruses do
not penetrate the blood-brain barrier, but exceptions have been reported, and
related viruses cause disease in the central nervous system of animals. The
flu-like illness that often precedes the onset of CFS may either suppress
immune function, causing an increased viremia, and/or lower the blood-brain
barrier. In both cases the result may be that a virus already present in the
blood enters the brain. It is well known that zoonotic viruses typically are
more malignant than viruses with a long history of host-virus evolution.
Similarly, a virus reaching an unfamiliar organ may cause particular
problems.

Studying the effects of mobile phone use on the auditory system and the central nervous system: a review of the literature and future directions.

Eur Arch Otorhinolaryngol. 2008 Sep;265(9):1011-9. Epub 2008 May 27.Click here to read Links

Studying the effects of mobile phone use on the auditory system and the central nervous system: a review of the literature and future directions.

http://www.ncbi.nlm.nih.gov/pubmed/18504596?ordinalpos=23&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Department of Otorhinolaryngology, Head and Neck Surgery, University of Crete School of Medicine, University Hospital of Crete, 71110, Heraklion, Crete, Greece, antinik@yahoo.com.

The wide spread of mobile communication since the late 1980 s raises questions about the effects of electromagnetic fields (EMFs) on the human body. Most studies have focused on the non-thermal effects of electromagnetic radiation (EMR). Low-energy EMFs seem to cause structural and functional changes in the cell membrane of different cell types, leading to abnormal cell response. Such changes within the central nervous system (CNS) and auditory system, which directly receive EMR during mobile phone use, are of particular interest. Various studies suggest that EMR directly affects neurons by reducing the neuronal reactivity, increasing the neural membrane conductivity and prolonging their refractory period. Furthermore, although it has been suggested that EMR is related with increased incidence of specific tumors and can interact with known carcinogenic agents, no conclusive evidence exists supporting its role in carcinogenesis. Therefore, no safe conclusions can be drawn regarding the potential harmful effects of mobile phone use. Experiments are underway by our laboratory to investigate possible effects of mobile phone use on the auditory system and the CNS. These along with other studies are expected to further clarify whether mobile phone use truly presents a health hazard.

PMID: 18504596 [PubMed - in process]

'What the Nose Knows' by Avery Gilbert: An olfactory specialist looks at the smelly side of life

We posted the below comment in the comments at the newspaper where this story was published. We encourage others to share their scientifically based comments as well.
Comment: Avery Gilbert is to the MCS community as Michael Savage was to the autism community. It would seem Gilbert has missed literally hundreds of studies out there showing various biological alterations that account for MCS symptoms. Another case of HITSD (head-in-the-sand disorder), unless Gilbert has industry ties to explain his denial. It would be interesting to know whether he has any industries ties which have not been disclosed that stand behind the promotion of this propaganda. Sure enough the first hit on him in a Google search shows he's the president of Synesthetics, Inc., a firm which "provides innovative sensory science for the development and marketing of consumer products... We help our clients measure and optimize the multisensory impact of fragrance on consumer perception... We put sensory science in the service of marketing... Synesthetics, Inc. brings proven sensory research expertise to the challenges of designing, evaluating, and marketing fragranced products." Enough said... Gilbert is not a medical doctor, has no credibility to determine what causes MCS, and is obviously protecting his financial interests in consumer products scientifically proven to be laden with toxic substances. Anne Steinemann, on the other hand, has published independent, peer-reviewed data that shows the very products Gilbert is protecting indeed emit carcinogens and numerous unlabeled chemical ingredients, many of which are on the Environmental Protection Agency (EPA) no safe limit list, meaning no exposure level no matter how small is considered safe.

Steinemann AC. Fragranced consumer products and undisclosed ingredients. Environ Impact Asses Rev (2008), doi:10.1016/j.eiar.2008.05.002. http://www.ce.washington.edu/people/faculty/bios/documents/Steinemann2008.pdf


'What the Nose Knows' by Avery Gilbert: An olfactory specialist looks at the smelly side of life
http://www.dallasnews.com/sharedcontent/dws/ent/stories/DN-bk_nose_0810gl.ART.State.Bulldog.4d59380.html


There he examines the syndrome known as Multiple Chemical Sensitivity or Idiopathic Environmental Intolerance.

The verdict: The symptoms are real but psychosomatic. "The psychogenic hypothesis doesn't sit well with some IEI patients ... [T]hey resent any suggestion that ... implies their suffering isn't real. The good news for them, if they will only hear it, is that the psychogenic hypothesis points to a treatment."

Friday, August 8, 2008

Fibromyalgia syndrome: a relevant recent construction of an ancient condition?

Curr Opin Support Palliat Care. 2008 Jun;2(2):122-7.

Fibromyalgia syndrome: a relevant recent construction of an ancient condition?

http://www.ncbi.nlm.nih.gov/pubmed/18685409?dopt=AbstractPlus

Service de Médecine Interne et Centre de la Douleur, Hôtel-Dieu, Paris, France. serge.perrot@htd.aphp.fr

PURPOSE OF REVIEW: Fibromyalgia is considered the most common chronic pain syndrome. This syndrome is poorly understood and not widely accepted as a distinct clinical entity but an increasing number of pharmacological and nonpharmacological treatments are being developed for its management. RECENT FINDINGS: The clinical description of fibromyalgia is now well established, but controversies on diagnostic criteria are increasing. Pathophysiological studies suggest that fibromyalgia is a painful rheumatic disorder in which pain primarily stems from central sensitization and from other neuronal changes, including alterations in peripheral neuronal systems. Central sensitization may also underlie associated symptoms, including anxiety, sleep disorders, fatigue, and other dysfunctions such as irritable bowel syndrome and bladder instability.Several agents, including serotonin-norepinephrine reuptake inhibitors (duloxetine and milnacipran), weak opioids (tramadol), and anticonvulsants (pregabalin), as well as nonpharmacological approaches, have been recently evaluated in clinical trials, demonstrating benefit in terms of pain reduction and improvement of core symptoms (i.e., fatigue and sleep disturbance). SUMMARY: Despite the fact that pathophysiology and diagnostic criteria remain unclear, the level of scientific data collected on this recently described condition should convince clinicians of the existence of this syndrome, allowing improved management of the many patients suffering from chronic pain.

PMID: 18685409 [PubMed - in process]

Treating Chronic Fatigue states as a disease of the regulation of energy metabolism.

Med Hypotheses. 2008 Aug 4. [Epub ahead of print]

Treating Chronic Fatigue states as a disease of the regulation of energy metabolism.

http://www.ncbi.nlm.nih.gov/pubmed/18684570?dopt=AbstractPlus

Delta G Ltd, 37 The Moor, Melbourn, Royston, Herts SG8 6ED, UK.

Chronic Fatigue Syndrome is a physiological state in which the patient feels high levels of fatigue without an obvious organic cause, which affects around 1 in 400 people in the developed world. A wide range of causes have been suggested, including immune or hormonal dysfunction, viral or bacterial infection, and psychological somatization. It is likely that several causes are needed to trigger the disease, and that the triggers are different from the mechanisms that maintain fatigue over months or years. Many treatments have been tested for CFS, with very limited success - a programme of combined CBT and graded exercise shows the most effect. I suggest that patients with CFS have a reduced ability to increase mitochondrial energy production when exertion requires it, with fewer mitochondria that are each more efficient, and hence nearer to their maximum energy output, than normal. A range of indirect evidence suggests that the renin-angiotensin system stimulates mitochondrial responsiveness and reduces mitochondrial efficiency: chronic under-stimulation of this system could contribute to CFS aetiology. If correct, this means that CFS can be successfully treated with RAS agonists (eg angiotensin mimetics), or adrenergic agonists. It also suggests that there will be a positive link between the use of adrenergic- and RAS-blocking drugs and CFS incidence, and a negative link between adrenergic agonist use and CFS.

PMID: 18684570 [PubMed - as supplied by publisher]

Increased oxidative stress suggested by low serum vitamin E concentrations in patients with chronic fatigue syndrome

Increased oxidative stress suggested by low serum vitamin E concentrations in patients with chronic fatigue syndrome.

Journal: Int J Cardiol. 2008 Aug 4. [Epub ahead of print]

Authors: Miwa K, Fujita M.

Affiliation: Department of Internal Medicine, Nanto Home and Regional
Medical Center, 577 Matsubara, Nanto, Toyama 939-1518, Japan.

NLM Citation: PMID: 18684522

Serum alpha-tocopherol concentrations were determined in 50 patients
with chronic fatigue syndrome (CFS) and 40 control subjects (Control).

Prevalence of each or any coronary risk factor was not significantly
different between CFS and Control. CFS had significantly lower
alpha-tocopherol concentrations than Control. The concentrations were
significantly lower in the subjects with any coronary risk factors
than those without in CFS as well as Control. Even among the subjects
with any coronary risk factors and also among those without, CFS had
significantly lower alpha-tocopherol concentrations than Control.

In conclusion, CFS had significantly lower alpha-tocopherol
concentrations irrespective of coronary risk factors than Control,
suggesting the presence of increased oxidative stress in CFS.

NEWS, Science, & Links Summary for the W/E 8/8/2008

August 8, 2008

Athletes are concerned about Beijing's air -- and with reason
http://sportsillustrated.cnn.com/2008/olympics/2008/writers/david_epstein/08/08/beijing.pollution2/?eref=sircrc

Orange County cities review ban on fake grass
http://www.latimes.com/news/local/la-me-fakegrass8-2008aug08,0,3908261,print.story

'Alarming' elevated cancer risk in South Seattle linked to air pollution
http://seattlepi.nwsource.com/local/374066_badair08.html

Local hospitals urged to phase out mercury
http://www.gmanews.tv/story/112356/Local-hospitals-urged-to-phase-out-mercury

Baby boy dies after DPT vaccination

http://timesofindia.indiatimes.com/Hyderabad/Baby_boy_dies_after_DPT_vaccination_/articleshow/3340464.cms

August 7, 2008

Environmental chemists keep watchful eye on Beijing's smog
http://www.nature.com/news/2008/080807/full/news.2008.1024.html

Toxic Lawns
http://www.kimatv.com/news/26394129.html

E. Hanover residents: Power line may risk our health
http://www.dailyrecord.com/apps/pbcs.dll/article?AID=/20080807/COMMUNITIES14/808070341/1005/NEWS01

August 6, 2008

Battle over chemical-exposure legislation
http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2008/08/06/BAFE123KKR.DTL&type=science

New flame retardants detected in indoor and outdoor environments
http://pubs.acs.org/cgi-bin/sample.cgi/esthag/asap/html/es802145r.html

Survey finds many Americans believe air inside their homes is cleaner
than outdoor air
http://www.environmental-expert.com/resulteachpressrelease.aspx?cid=28518&codi=35490&loginemail=admin@mcs-america.org&logincode=134018

Fibromyalgia: Unreal or Misunderstood?
http://www.americanchronicle.com/articles/70552

Man sues T-Mobile, Motorola, and Samsung over cellphone radiation health
effects
http://www.intomobile.com:80/2008/08/06/man-sues-t-mobile-motorola-and-samsung-over-cellphone-radiation-health-effects.html

Bill would charge fees at ports for cleaner air
http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2008/08/06/BAFV125L5A.DTL

Eco-bulbs may be harmful
http://digital.asiaone.com/Digital/News/Story/A1Story20080806-80848.html

August 5, 2008

New cellphone health litigation surfaces in California court
http://www.rcrnews.com/article/20080805/WIRELESS/778854624/1078/778854624

All natural baby info
http://www.canada.com/surreynow/news/story.html?id=27b3fa6c-73fd-451b-bb47-c762d3201cd4

EPA and State of California consider ban on PFOA, often used in nonstick
packaging
http://www.packagingdigest.com/article/CA6584415.html

Using acupuncture to treat pain is catching on
http://www.goupstate.com/article/20080805/NEWS/808050307/0/SPORTS04

Crunch time for peanut allergies
http://www.independent.co.uk/life-style/health-and-wellbeing/features/crunch-time-for-peanut-allergies-885074.html

It's a small, small world
http://www.startribune.com/lifestyle/health/26249409.html?location_refer=Lifestyle

UC Davis study: Agent Orange exposure doubles veterans' likelihood of
getting prostate cancer
http://www.sacbee.com/health/story/1132599.html

Studies show citrus rinds offer new twist on toxin removal
http://www.sun-sentinel.com/business/sfl-0805econugenics,0,645140.story

Chemical discovery on Mars stumps Phoenix team
http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2008/08/05/MN0G1253QT.DTL

USA Today: Toxic Legacy, Can a Plastic Alter Human Cells?
http://www.usatoday.com/news/health/2008-08-04-toxic-plastics-main_N.htm

EU metals and chemical law not huge burden-official
http://www.guardian.co.uk/business/feedarticle/7702469

Herbicide residues: the ground is the child's breathing zone
http://www.brantfordexpositor.ca/ArticleDisplay.aspx?e=1142553

August 4, 2008

California Considers Banning PFOAs
http://www.greenrightnow.com/2008/08/04/california-considers-banning-pfoas/

Air Quality Tested In Portable Classrooms
http://www.newschannel5.com/Global/story.asp?S=8786989

Fibromyalgia/CFS Support Group
http://www.loudountimes.com/events/1157/

USA TODAY asked experts how parents can avoid hormone-like chemicals in
children's products.
http://www.usatoday.com/money/industries/retail/2008-08-04-toxic-toys-questions_N.htm

Let's Get the Lead Out, EPA
http://www.utne.com/2008-08-04/Environment/Lets-Get-the-Lead-Out-EPA.aspx?blogid=26

New car smell: Intoxicating or toxic?
http://latimesblogs.latimes.com/uptospeed/2008/08/new-car-smell-i.html

Smog returns to Beijing, blue sky disappears
http://www.nzherald.co.nz/section/7/story.cfm?c_id=7&objectid=10525166&pnum=0

Popular Pesticides More Dangerous Than You Think
http://www.redorbit.com/news/science/1508789/popular_pesticides_more_dangerous_than_you_think/

Disability Support Groups
http://www.rocklintoday.com/news/templates/disabilities.asp?articleid=6418&zoneid=64

Is that keyboard toxic? Nanotechnology promises countless benefits, but at
what risk?
http://www.computerworld.com/action/article.do?command=viewArticleBasic&taxonomyName=management&articleId=9110396&taxonomyId=14&intsrc=kc_feat

Health Tip: Get Rid of Allergens
http://health.usnews.com/articles/health/healthday/2008/08/04/health-tip-get-rid-of-allergens.html

N.D. project collects toxic farm chemicals
http://www.in-forum.com/articles/index.cfm?id=210352&section=News&freebie_check&CFID=64789176&CFTOKEN=35690166&jsessionid=8830bc7858a11b3a7728

August 3, 2008

Attempt to Ban Aspartame 'Poison' From Food, Drink
http://en.epochtimes.com/n2/new-zealand/aspartame-951-ban-poison-2093.html

Lost in a System Where Doctors Don't Want to Listen
http://www.washingtonpost.com/wp-dyn/content/article/2008/08/01/AR2008080102953_pf.html

Green Ways to Be Bug-Free
http://www.washingtonpost.com/wp-dyn/content/article/2008/07/31/AR2008073102718.html

Woman faces battle with fatigue
http://www.poughkeepsiejournal.com/apps/pbcs.dll/article?AID=/20080803/NEWS06/808030330

August 2, 2008


Forget the fragrance
http://www.sfgate.com/columnists/evans/

Ca. Acrylamide Settlement Will Reduce Chemical in Potato Chips
http://www.efluxmedia.com/news_Ca_Acrylamide_Settlement_Will_Reduce_Chemical_in_Potato_Chips_21398.html

Chinese try to sniff out pollution before Games
http://www.ctv.ca/servlet/ArticleNews/story/CTVNews/20080802/human_sniffers_080802/20080802?s_name=beijing2008

Get Ready to Itch and Sneeze: A warmer planet could mean we'll suffer more
(and stronger) allergies.
http://www.newsweek.com/id/150502

Ottawa linked to cellphone lobbyists
http://www.thestar.com/News/Canada/article/471613

August 1, 2008

Residents blame apartment complex for making them sick
http://www.wdbj7.com/Global/story.asp?S=8771291&nav=S6aK

Residents blame apartment complex for making them sick
http://www.wdbj7.com/Global/story.asp?S=8771291&nav=S6aK

US takes on toxic toys
http://www.businessgreen.com/business-green/news/2223077/takes-toxic-toys

August 2008

Floral Scents Going Off the Air?
http://www.ehponline.org/docs/2008/116-8/forum.html#flor

Links

The Center for Health, Environment and Justice
Back-to-School Guide to PVC-Free School Supplies
http://www.besafenet.com/pvc/documents/Back%20to%20School%20Guide%20to%20PVC%20Free%20School%20Supplies.pdf

Scientific Studies

A psychophysical study of auditory and pressure sensitivity in patients with
fibromyalgia and healthy controls.
http://www.ncbi.nlm.nih.gov/pubmed/18280211?dopt=AbstractPlus

Temporal Trends of Synthetic Musk Compounds in Mother's Milk and
Associations with Personal Use of Perfumed Products
http://pubs.acs.org/cgi-bin/abstract.cgi/esthag/asap/abs/es800626n.html

Genetic variations associated with interindividual sensitivity in the
response to arsenic exposure.
http://www.ncbi.nlm.nih.gov/pubmed/18681785?dopt=AbstractPlus

[Neuropsychological performance in patients with fibromyalgia syndrome:
Relation to pain and anxiety.]
http://www.ncbi.nlm.nih.gov/pubmed/18674438?dopt=AbstractPlus

Effects of Concurrent Strength and Endurance Training on Physical Fitness
and Symptoms in Postmenopausal Women With Fibromyalgia: A Randomized
Controlled Trial.
http://www.ncbi.nlm.nih.gov/pubmed/18675392?dopt=AbstractPlus

Toxic effects of DDT and methyl mercury on the hepatocytes from Hoplias
malabaricus.
http://www.ncbi.nlm.nih.gov/pubmed/18675336?dopt=AbstractPlus

Lourdes Salvador
www.mcs-america.org

Disclaimer:
Articles and links are not necessarily the opinion of MCS America, Lourdes
Salvador, and/or the volunteers who assemble this information. We will be
not responsible for misuse of this information. Posting does not constitute
endorsement. We have no financial interest in anything posted . This post is
provided free of charge via volunteer effort.

Wednesday, August 6, 2008

Wolk calls chemical industry media blitz against baby bottle bill "toxic to the process"

Wolk calls chemical industry media blitz against baby bottle bill "toxic to the process"

Assemblywoman Lois Wolk, D-Davis, has blasted a media campaign run by the American Chemistry Council to sway key legislators' votes on legislation to restrict the chemical Bisphenol A in plastic baby bottles and other baby food containers. Wolk called the misleading campaign counterproductive and "toxic to the political process."

"This is exactly the kind of deceptive lobbying tactic that I've been fighting since the day I arrived in the Legislature. It's toxic to the political process," said Wolk, describing mailers sent in her district with an image of an empty shopping cart and claiming that if SB 1713 is passed "your favorite products may soon disappear."

<snip>

See the link for the full story.

Wolk calls chemical industry media blitz against baby bottle bill "toxic to the process"

Wolk calls chemical industry media blitz against baby bottle bill "toxic to the process"

Assemblywoman Lois Wolk, D-Davis, has blasted a media campaign run by the American Chemistry Council to sway key legislators' votes on legislation to restrict the chemical Bisphenol A in plastic baby bottles and other baby food containers. Wolk called the misleading campaign counterproductive and "toxic to the political process."

"This is exactly the kind of deceptive lobbying tactic that I've been fighting since the day I arrived in the Legislature. It's toxic to the political process," said Wolk, describing mailers sent in her district with an image of an empty shopping cart and claiming that if SB 1713 is passed "your favorite products may soon disappear."

<snip>

See the link for the full story.

Tuesday, August 5, 2008

[Neuropsychological performance in patients with fibromyalgia syndrome: Relation to pain and anxiety.]

Psicothema. 2008 Aug;20(3):427-31.

[Neuropsychological performance in patients with fibromyalgia syndrome: Relation to pain and anxiety.]

http://www.ncbi.nlm.nih.gov/pubmed/18674438?dopt=AbstractPlus

[Article in Spanish]

Universidad Pablo de Olavide.

Neuropsychological performance in patients with fibromyalgia syndrome: Relation to pain and anxiety. Previous studies have revealed the presence of cognitive impairment in patients with fibromyalgia syndrome (FMS). However, they have not determined the possible influence of the diverse clinical variables in these disturbances. The first aim of the current study is to compare the cognitive function of 81 patients with FMS and 35 healthy controls by means of a neuropsychological battery. The second aim is to determine the influence of anxiety and pain in the cognitive impairment of patients with FMS. The results of our study show that patients with FMS display a significantly lower cognitive performance and a significantly higher anxiety level than the healthy controls in all the parameters assessed. The neuropsychological performance in patients with FMS is associated with pain, and this relation was independent of the anxiety level. The relationship between cognitive performance and anxiety level was also significant. Therefore, we conclude that cognitive performance is primarily affected by pain. The level of anxiety explains part of the variability in neuropsychological tests that is not explained by pain.

PMID: 18674438 [PubMed - in process]

Toxic effects of DDT and methyl mercury on the hepatocytes from Hoplias malabaricus.

Toxicol In Vitro. 2008 Jul 15. [Epub ahead of print]

Toxic effects of DDT and methyl mercury on the hepatocytes from Hoplias malabaricus.

http://www.ncbi.nlm.nih.gov/pubmed/18675336?dopt=AbstractPlus

Departamento de Biologia Celular, Universidade Federal do Paraná, Cx. Postal 19031, CEP 81.531-990 Curitiba, PR, Brazil.

Here, we examined the impact of dichlorodiphenyltrichloroethane (DDT) and monomethyl mercury (MeHg) on the redox milieu and survival of hepatocytes from Hoplias malabaricus (traíra). After isolation and attachment of cells, we established one control and four treatments: DDT (50nM of DDT), MeHg I (0.25muM of MeHg), MeHg II (2.5muM of MeHg) and DDT*MeHg I (combination of 50nM of DDT and 0.25muM of MeHg). After four days the exposed hepatocytes presented significantly increased damage in lipids (all treatments), proteins (DDT*MeHg I and MeHg II) and reduced cell viability (all treatments). Also the antioxidant enzymes catalase, glucose-6-phosphate dehydrogenase (G6PDH), glutathione reductase and superoxide dismutase were affected. The current data showed that despite of some protective responses, the increased disturbs on membrane lipids and proteins, increased hydrogen peroxide levels, and decreased glutathione concentration and cell viability strongly indicate oxidative stress as the reason of hepatotoxicity due to DDT and MeHg exposure. In addition, DDT and MeHg together had greater effect than alone when G6PDH and glutathione-S-transferase activities and lipids damage were considered. These findings are indicative of hepatotoxicity occurring at realistic concentrations of DDT and MeHg found in Amazonian fish tissues.

PMID: 18675336 [PubMed - as supplied by publisher]

Sunday, August 3, 2008

NEWS & COMMENT: Lost in a System Where Doctors Don't Want to Listen

Comment:  This is a well-written article examining some of the issues people with  unexplained illnesses face in the medical profession.  Aside from the "disbelief" that many doctors give unexplained conditions, this article is an eye opener to other factors such as the economics and workload issues behind tossing these patients to the wayside.  Dr. Natelson gives some advice as to how to handle this as he feels it's only going to get worse.  He has some interesting insights.  I highly recommend reading the full text at the link below.
 
Lost in a System Where Doctors Don't Want to Listen

By Benjamin H. Natelson
Sunday, August 3, 2008; B03

I'd like to tell you about one of my patients. She's the kind of patient that I enjoy seeing but that many doctors go out of their way to avoid. This means that she's also the kind of patient I worry about most -- a patient who in the near future may be stranded without proper care as fewer and fewer doctors, constrained by time and the economics of our health care system, are willing to perform the fundamental task of diagnosing difficult or unclear medical problems.

Saturday, August 2, 2008

Prefrontal cortex oxygenation during incremental exercise in chronic fatigue syndrome

Prefrontal cortex oxygenation during incremental exercise in chronic fatigue syndrome.

Journal: Clin Physiol Funct Imaging. 2008 Jul 29. [Epub ahead of print]

Authors: J. Patrick Neary [1], Andy D. W. Roberts [2], Nina Leavins
[2], Michael F. Harrison [1], James C. Croll [2] and James R.  Sexsmith [2]

Affiliations:
[1] Faculty of Kinesiology & Health Studies, University of Regina,
Regina, SK, Canada and

[2] Faculty of Kinesiology, University of New Brunswick, Fredericton NB, Canada

Correspondence to J. Patrick Neary, PhD, Faculty of Kinesiology &
Health Studies, University of Regina, Regina, SK, Canada S4S 0A2
E-mail: <patrick.neary@uregina.ca>

Affiliation: Faculty of Kinesiology & Health Studies, University of
Regina, Regina, SK, Canada.

NLM Citation: PMID: 18671793

This study examined the effects of maximal incremental exercise on
cerebral oxygenation in chronic fatigue syndrome (CFS) subjects.
Furthermore, we tested the hypothesis that CFS subjects have a
reduced oxygen delivery to the brain during exercise.

Six female CFS and eight control (CON) subjects (similar in height,
weight, body mass index and physical activity level) performed an
incremental cycle ergometer test to exhaustion, while changes in
cerebral oxy-haemoglobin (HbO(2)), deoxy-haemoglobin (HHb), total
blood volume (tHb = HbO(2) + HHb) and O(2) saturation [tissue
oxygenation index (TOI), %)] was monitored in the left prefrontal
lobe using a near-infrared spectrophotometer. Heart rate (HR) and
rating of perceived exertion (RPE) were recorded at each workload
throughout the test.

Predicted VO(2peak) in CFS (1331 +/- 377 ml) subjects was
significantly (P </= 0.05) lower than the CON group (1990 +/- 332
ml), and CFS subjects achieved volitional exhaustion significantly
faster (CFS: 351 +/- 224 s; CON: 715 +/- 176 s) at a lower power
output (CFS: 100 +/- 39 W; CON: 163 +/- 34 W). CFS subjects also
exhibited a significantly lower maximum HR (CFS: 154 +/- 13 bpm; CON:
186 +/- 11 bpm) and consistently reported a higher RPE at the same
absolute workload when compared with CON subjects. Prefrontal cortex
HbO(2), HHb and tHb were significantly lower at maximal exercise in
CFS versus CON, as was TOI during exercise and recovery. The CFS
subjects exhibited significant exercise intolerance and reduced
prefrontal oxygenation and tHb response when compared with CON subjects.

These data suggest that the altered cerebral oxygenation and blood
volume may contribute to the reduced exercise load in CFS, and
supports the contention that CFS, in part, is mediated centrally.

Friday, August 1, 2008

NEWS, Science, & Links Summary for the W/E 8/1/2008

August 1, 2008

All About Formaldehyde
http://www.buildinggreen.com/auth/article.cfm/2008/7/29/All-About-Formaldehyde/

Pesticides, pollutants threaten Canadian tap water, researchers suggest
http://www.cbc.ca/health/story/2008/08/01/water-pesticides.html

Phthalates: Are the chemicals that make plastic bendy a health hazard?
http://www.cbc.ca/health/story/2008/06/04/f-phthalates.html

WASA Lead Test Procedure Gives False Readings, Groups Say
www.washingtonpost.com/wp-dyn/content/article/2008/08/01/AR2008080102964.htm

Popular pesticides more dangerous than you think: Poisonings, even deaths,
tied to 'safe' house, farm chemicals.
http://articles.lancasteronline.com/local/4/225335

All About Formaldehyde
http://www.buildinggreen.com/auth/article.cfm/2008/7/29/All-About-Formaldehyde/

July 31, 2008

Shield our students
http://www.bclocalnews.com:80/richmond_southdelta/southdeltaleader/opinion/letters/26159259.html

Chemicals found
http://www.bclocalnews.com/richmond_southdelta/southdeltaleader/news/26158959.html

Neighbors: Apartment Mold Causing Sickness
http://www.kptv.com/houseandhome/17049370/detail.html

Don't inhale that new car smell
http://www.cnn.com/2008/LIVING/wayoflife/07/31/aa.new.car.smell/

TWO 'TOXIC SOFA' CLAIMS - A WEEK
http://www.thisisleicestershire.co.uk/displayNode.jsp?nodeId=132384&command=displayContent&sourceNode=232710&home=yes&more_nodeId1=132393&contentPK=21196782

Local company helps get toxic toys off the market
http://www.komonews.com/news/26168844.html

Congress sends Bush bill banning lead in children's products
http://www.latimes.com/news/nationworld/politics/wire/sns-ap-lead-in-toys,1,5533109.story

Industry ties to vaccine advocates raises skepticism
http://www.fiercebioresearcher.com/vaccines/story/industry-ties-vaccine-advocates-raises-skepticism/2008-07-31

'Safe' Pesticides Now First in Poisonings
http://www.marketwatch.com/news/story/safe-pesticides-now-first-poisonings/story.aspx?guid=%7BCD2CEF81-9F71-402B-8DCC-5322339B39AB%7D&dist=hppr

Report: Lead not a problem on fields.
http://www.goerie.com/apps/pbcs.dll/article?AID=/20080731/NEWS02/807310431/-1/NEWS

The air in Beijing is still dirty, and the Olympic planners aren't happy
about it.
http://blogs.nature.com/news/thegreatbeyond/2008/07/beijing_smog_story_here.html

Asbestos maker ordered to hold talks with retired workers' union over toxic
side effects
http://mdn.mainichi.jp/national/archive/news/2008/07/31/20080731p2a00m0na014000c.html

July 30, 2008

Smoking Ban Slashes Cardiac Hospitalizations
http://www.medpagetoday.com/PrimaryCare/Smoking/tb/10335?pfc=101&spc=235

Burning joss sticks 'as deadly as traffic fumes or cigarette smoke'
http://www.guardian.co.uk/world/2008/jul/30/health

Living near freeway could harm pregnant women: study
http://www.nationalpost.com/news/canada/story.html?id=690782

The filthy air conundrum
http://news.bbc.co.uk/2/hi/uk_news/magazine/7532603.stm

Oregon accounts for 40 million pounds of herbicides, insecticides
http://blog.oregonlive.com/breakingnews/2008/07/oregon_accounts_for_40_million.html

Government pesticide and fertilizer data dropped
http://pubs.acs.org/cgi-bin/sample.cgi/esthag/asap/html/es801937k.html

Carcinogen worries stick to food packaging
http://www.latimes.com/business/la-fi-lazarus30-2008jul30,1,279380.column

July 29, 2008

Prenatal Cell Phone Exposure Tied to Behavior
http://www.nytimes.com/reuters/technology/tech-prenatal-cell-phone.html

Physician's Professional Mission is to 'Get the Lead Out!'
http://www.marketwatch.com/news/story/physicians-professional-mission-get-lead/story.aspx?guid=%7B760BD5EA-7331-4DAF-BC4A-1C55A54EAE8C%7D&dist=hppr

Cell phone use can become an unhealthy obsession
http://www.thespectrum.com/apps/pbcs.dll/article?AID=/20080729/OPINION/807290328

Groups file suit over pesticide use
http://www.montereyherald.com/local/ci_10030315?nclick_check

Cut children's fluoride exposure, report to Health Canada urges
http://www.theglobeandmail.com/servlet/story/RTGAM.20080729.wfluoride29/BNStory/specialScienceandHealth/home?cid=al_gam_mostview

EPA tells staff don't talk
http://ap.google.com/article/ALeqM5iug4JpO54gzlHe2EdnXHEGTEKreQD9270MO81

Lawmakers Agree to Ban Toxins in Children's Items
http://www.washingtonpost.com/wp-dyn/content/article/2008/07/28/AR2008072802586_pf.html

Toxic fragrances in air fresheners & laundry detergent
http://www.tampabays10.com/news/health/story.aspx?storyid=85957&catid=12

U.S. Congress Looks To Ban Toxic Chemicals From Children's Toys
http://www.allheadlinenews.com/articles/7011758640

Baby kept in mortuary for 21 years
http://ukpress.google.com/article/ALeqM5id_R4OTxjLgvAGNFvriCp3d9jtxg

Silver fillings source of growing debate
http://www.clarionledger.com/apps/pbcs.dll/article?AID=/20080729/HEALTH/807290331/1242/health

July 28, 2008

Fibromyalgia and the Courts: Here Comes the Judge
http://www.healthcentral.com/chronic-pain/c/91/35342/fibromyalgia/pf/

Suspend wi-fi in schools, says union chief following reports it causes
ill-health
http://www.dailymail.co.uk/news/article-1039235/Suspend-wi-fi-schools-says-union-chief-following-reports-causes-ill-health.html

'New car smell' becoming less toxic, report says
http://news.cnet.com/8301-11128_3-10001060-54.html?hhTest=1

OSU Study Shows Exposure ot Bad Air Raises Blood Pressure
http://researchnews.osu.edu/archive/rajagop.htm

Dangerous Baby Products
http://www.news4jax.com/news/17011201/detail.html

July 27, 2008

POPULATIONS EXPOSED TO ENVIRONMENTAL URANIUM: Increased Risk of Infertility
and Reproductive Cancers!
http://gregornot.wordpress.com/2008/07/27/populations-exposed-to-environmental-uranium/

Air fresheners contain toxic compounds
http://www.presstv.ir/detail.aspx?id=64952&sectionid=3510210

New frontiers in autism research
http://www.fosters.com/apps/pbcs.dll/article?AID=/20080727/GJCOMMUNITY_01/460263527

Mother: 'We're not waiting for the government'
http://www.fosters.com/apps/pbcs.dll/article?AID=/20080727/GJCOMMUNITY_01/724229661

Products' scents may hide toxic secrets
http://www.chicagotribune.com/news/nationworld/chi-toxic_for_final_27jul27,0,637363.story

His business was, well, perfectly natural
http://www.boston.com/news/local/articles/2008/07/27/his_business_was_well_perfectly_natural/?page=full

Home buyers should check for hidden and buried toxins
http://www.latimes.com/business/la-re-enviro27-2008jul27,0,3518170.story

July 26, 2008

Autism Rates Soaring For Somalis In U.S.
http://cbs4.com/health/somali.community.autism.2.780617.html

Toxic Chemicals Make Top Household, Laundry Products Smell Clean
http://medheadlines.com/2008/07/26/toxic-chemicals-make-top-household-laundry-products-smell-clean/

Democrat Vows Bill to Block 'Secret Rule' on Workplace Toxins
http://www.washingtonpost.com/wp-dyn/content/article/2008/07/25/AR2008072500595.html?referrer=emailarticle

New Car Smell
http://www.poughkeepsiejournal.com/apps/pbcs.dll/article?AID=/20080726/LIFE12/80725026/1005/LIFE

Is your makeup killing you?
http://www.mydesert.com/apps/pbcs.dll/article?AID=/20080726/LIFESTYLES03/807260306/1059/lifestyles03

Fragrances May Emit Potential Toxins
http://www.webmd.com/news/20080725/fragrances-may-emit-potential-toxins?page=2

Finding a way through the pain
http://www.dailypress.com/features/dp-life_chronicfatigue_0726jul26,0,2051482.story

July 25, 2008

Where the mould grows
http://www.theglobeandmail.com/servlet/story/RTGAM.20080725.wbcmould2607/BNStory/National/home/?pageRequested=all

Health Hazards in Household Cleaners Exposed
http://www.cbc.ca/cp/HealthScout/080725/6072513AU.html

Too Young for a Cell Phone
http://www.ens-newswire.com/ens/jul2008/2008-07-25-01.asp

Children become ill after mistaking 'Fruit Bomb' air freshener for candy
http://www.buffalonews.com/home/story/399616.html

Study: Fragrant compound in household products harms lungs
http://abclocal.go.com/wls/story?section=news/health&id=6287687

EPA Tests For Toxic Fumes At Day Care Center
http://www.ktvu.com/news/16989098/detail.html

Neighbors: Sprayed Yard a 'Toxic Dump' County is asked to help
http://www.emporiagazette.com/news/2008/jul/25/neighbors_sprayed_yard/

EPA Checks East Bay Homes, Businesses For Toxic Substances
http://www.nbc11.com/newsarchive/16988192/detail.html

Nanotechnology: Really, really small stuff that's really big
http://www.cbc.ca/health/story/2008/07/25/f-nanotech-health.html

Clock ticking for US nanotech companies
http://www.nature.com/news/2008/080725/full/news.2008.983.html

Veterans get ALS disability: 'Lou Gehrig's disease' to be listed as
service-connected, U.S. says
http://www.baltimoresun.com/news/nation/bal-te.als25jul25,0,7448073.story

Environmental Group Calls Triclosan a Ubiquitous Menace
http://www.medpagetoday.com/PublicHealthPolicy/EnvironmentalHealth/tb/10269

Toxic baby bottles and kids' products?
http://abclocal.go.com/kabc/story?section=news/health&id=6288134

July 24, 2008

Toxic Chemicals Found in Laundry Soaps and Air Fresheners
http://www.livescience.com/health/080724-toxic-laundry.htm

Household Products: Start with labels
http://seattlepi.nwsource.com/opinion/372109_scented.html

Cement plants spew toxic mercury
http://www.arcamax.com/technology/s-383361-633979

One Pesticide Classified as Unsafe, Hundreds More to Go
http://www.commondreams.org/news2008/0724-19.htm

July 23, 2008

UW researcher: Toxic scents hiding in air fresheners, detergents
http://www.komonews.com/news/health/25836839.html

July 17, 2008

Color Me Concerned
http://www.baltimoresun.com/news/health/bal-to.hs.additive17jul17,0,7293307,print.story

July 16, 2008

Woman receives diagnosis for allergy to electricity
http://www.thewesternstar.com/index.cfm?sid=153192&sc=25

Links

Repeal Existing Stereotypes for Chronic, Immunological and Neurological
Diseases (RESCIND)
http://www.rescindinc.org/

Scientific Studies

Self-reported differences in empowerment between lurkers and posters in
online patient support groups.
http://www.ncbi.nlm.nih.gov/pubmed/18653442?dopt=AbstractPlus

Effects of occupational pesticide exposure on children applying pesticides.
http://www.ncbi.nlm.nih.gov/pubmed/18662718?dopt=AbstractPlus

Characteristics and patterns of healthcare utilization of patients with
fibromyalgia in general practitioner settings in Germany.
http://www.ncbi.nlm.nih.gov/pubmed/18664319?dopt=AbstractPlus

Post-radiation syndrome as a NO/ONOO(-) cycle, chronic fatigue syndrome-like
disease.
http://www.ncbi.nlm.nih.gov/pubmed/18667279?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Glutathione S-transferase m1 and t1 null genotypes increase susceptibility
to idiosyncratic drug-induced liver injury.
http://www.ncbi.nlm.nih.gov/pubmed/18666253?dopt=AbstractPlus

Lourdes Salvador
www.mcs-america.org

Disclaimer:
Articles and links are not necessarily the opinion of MCS America, Lourdes
Salvador, and/or the volunteers who assemble this information. We will be
not responsible for misuse of this information. Posting does not constitute
endorsement. We have no financial interest in anything posted . This post is
provided free of charge via volunteer effort.

Post-radiation syndrome as a NO/ONOO(-) cycle, chronic fatigue syndrome-like disease.

Med Hypotheses. 2008 Jul 28. [Epub ahead of print]

Post-radiation syndrome as a NO/ONOO(-) cycle, chronic fatigue syndrome-like disease.

http://www.ncbi.nlm.nih.gov/pubmed/18667279?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

School of Molecular Biosciences, Washington State University, Pullman, WA 99164-4234, USA.

Post-radiation syndrome is proposed to be chronic fatigue syndrome (CFS) or a chronic fatigue syndrome-like illness, initiated by exposure to ionizing radiation. This view is supported by the nitric oxide/peroxynitrite (NO/ONOO(-)) cycle mechanism, the putative etiologic mechanism for CFS and related illnesses. Ionizing radiation may initiate illness by increasing nitric oxide levels via increased activity of the transcription factor NF-kappaB and consequent increased synthesis of the inducible nitric oxide synthase. Two types of components of the nitric oxide/peroxynitrite cycle have been studied in post-radiation syndrome patients and shown to be elevated. The symptoms and signs of post-radiation syndrome and its chronicity are similar or identical to those of chronic fatigue syndrome and can be explained as being a consequence of nitric oxide/peroxynitrite cycle etiology. While the data available to test this view are limited, it provides for the first time a comprehensive explanation for post-radiation syndrome.

PMID: 18667279 [PubMed - as supplied by publisher]

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