Increased oxidative stress suggested by low serum vitamin E concentrations in patients with chronic fatigue syndrome

Increased oxidative stress suggested by low serum vitamin E concentrations in patients with chronic fatigue syndrome.

Journal: Int J Cardiol. 2008 Aug 4. [Epub ahead of print]

Authors: Miwa K, Fujita M.

Affiliation: Department of Internal Medicine, Nanto Home and Regional
Medical Center, 577 Matsubara, Nanto, Toyama 939-1518, Japan.

NLM Citation: PMID: 18684522

Serum alpha-tocopherol concentrations were determined in 50 patients
with chronic fatigue syndrome (CFS) and 40 control subjects (Control).

Prevalence of each or any coronary risk factor was not significantly
different between CFS and Control. CFS had significantly lower
alpha-tocopherol concentrations than Control. The concentrations were
significantly lower in the subjects with any coronary risk factors
than those without in CFS as well as Control. Even among the subjects
with any coronary risk factors and also among those without, CFS had
significantly lower alpha-tocopherol concentrations than Control.

In conclusion, CFS had significantly lower alpha-tocopherol
concentrations irrespective of coronary risk factors than Control,
suggesting the presence of increased oxidative stress in CFS.