Potential human health risks from metals (Hg, Cd, and Pb) and polychlorinated biphenyls (PCBs) via seafood consumption: Estimation of target hazard quotients (THQs) and toxic equivalents (TEQs).
http://www.ncbi.nlm.nih.gov/pubmed/18584931?dopt=AbstractPlus
Pharmacological-Biological Department, Chemistry and Biochemistry Section, Medicine Veterinary Faculty, University of Bari, Strada Prov.le per Casamassima, km 3, 70010 Valenzano, BA, Italy.
Edible marine species (fish, cephalopod molluscs, crustaceans) from the Adriatic Sea were analyzed for content in heavy metals (Hg, Cd and Pb) and polychlorinated biphenyls (PCBs). Health risks to human via dietary intake of seafood were assessed by the target hazard quotients (THQs) and the toxic equivalent factors (TEFs). Mercury maximum concentrations corresponded to fish (0.07-1.56mugg(-1)w.w.), followed by cephalopod molluscs (0.10-0.55mugg(-1)w.w.), and crustaceans (0.27-0.33mugg(-1)w.w.). Cadmium levels in cephalopods (0.18-0.59mugg(-1)w.w.) were higher than those in fish (0.01-0.05mugg(-1)w.w.) and crustaceans (0.02-0.04mugg(-1)w.w.), while for Pb the concentrations were generally low (fish: ND-1.18mugg(-1)w.w., cephalopods: ND-0.17mugg(-1)w.w., crustaceans: ND-0.03mugg(-1)w.w.). For PCBs, concentrations in fish, cephalopods and crustaceans ranged between 141 and 3406ngg(-1)l.w., 190 and 542ngg(-1)l.w., and 202 and 429ngg(-1)l.w., respectively. Cd and Pb THQ values as well as estimates of PCB TEQ exposure indicated the absence of health risks through consumption of the various seafood. In contrast, mercury TEQs values due to consumption of certain fish species (albacore, rosefish and thornback ray) indicated that human health risk might be of concern.
PMID: 18584931 [PubMed - as supplied by publisher]
