| Allergol Int. 2007 Sep;56(3):313-6. Epub 2007 Jul 1. |
Three Cases of Ortho-phthalaldehyde-induced Anaphylaxis after Laryngoscopy: Detection of Specific IgE in Serum.
Suzukawa M, Komiya A, Koketsu R, Kawakami A, Kimura M, Nito T, Yamamoto K, Yamaguchi M.
Department of Allergy and Rheumatology, University of Tokyo Graduate School of Medicine.
Background: Ortho-phthalaldehyde (OPA) has recently been used as a disinfectant for various medical apparatuses. OPA is not generally recognized as a potential allergen. Case Summary: Subsequent to our recent report describing a patient presenting with OPA-induced anaphylaxis following laryngoscopy, we experienced two more such cases. In all three cases, the basophil histamine release test was useful for identifying the allergen as OPA. OPA-specific IgE was successfully detected in the serum of the patients by ELISA. Discussion: Physicians and co-medical workers need to be aware of potential allergens to which patients may be exposed during routine medical procedures.
PMID: 17582212 [PubMed - in process]
