Occupational Exposure to Dibutyl Phthalate Among Manicurists.
http://www.ncbi.nlm.nih.gov/pubmed/18545098?dopt=AbstractPlus
From the Department of Nursing (Ms Kwapniewski, Dr Kozaczka, Dr Duty), School for Health Studies, Simmons College; Department of Environmental Health (Drs Hauser, Duty), Environmental and Occupational Medicine and Epidemiology, Harvard School of Public Health, Boston, Mass; and National Center for Environmental Health (Drs Silva, Calafat), Centers for Disease Control and Prevention, Atlanta, Ga.
OBJECTIVE:: To measure manicurists' exposure to dibutyl phthalate (DBP) at work and to determine whether workplace characteristics influence this exposure. DBP is a reproductive and developmental toxicant in rats and is used in nail polish to hold color and prevent chipping. METHODS:: Pre- and postshift spot urine samples were collected from 40 manicurists. Linear regression compared the relationship between the log of the cross-shift differences in urinary phthalate monoester metabolite concentrations and use of workplace exposure control methods. RESULTS:: There was a statistically significant cross-shift increase of 17.4 ng/mL in the urinary concentration of mono-n-butyl phthalate, the major metabolite of DBP. Use of gloves reduced mono-n-butyl phthalate concentrations by 15.1 ng/mL below the preshift concentration compared with a 20.5 ng/mL increase if gloves were not worn. CONCLUSIONS:: Manicurists are occupationally exposed to DBP and glove use may minimize this exposure.
PMID: 18545098 [PubMed - as supplied by publisher]
